Abstract: Scientific and technological innovation is the fundamental driving force to promote social and economic development. However, the unbalanced and insufficient development of China's scientific and technological innovation resources aggravates the gap of the high-quality economic and industrial development between the eastern and western regions. Scientific and technological innovation in Sichuan focuses on the strategy of "One Mainstay, Multiple Support, Synergic Development in Five Districts", and has formed a regional collaborative pattern with Chengdu and Mianyang's scientific and technological innovation as the driving engines, making continuous contributions to local economy growth. At present, Sichuan Province, with good development opportunities of resources,platforms and global cooperation for scientific and technological innovation, should expand its cooperation and coordinated development with regional innovation highlands such as "Beijing-Tianjin-Hebei region", "Yangtze River Delta", and "Guangdong-Hong Kong-Macao Greater Bay Area", integrating its development into the national strategies such as "the Belt and Road Initiative", "Yangtze River Economic Belt" and "Chengdu-Chongqing Twin Cities Economic Circle",so as to build Sichuan into a pioneer province of innovation-driven development in an all-round way, and to promote the high-quality social and economic development of Sichuan.

Key words: Sichuan Province, scientific and technological innovation, regional development, local economy, high-quality development