Journal of Dali University ›› 2019, Vol. 4 ›› Issue (12): 75-78.

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Study on the Correlation among Focal Adhesion and Microfilaments and Cell Areas of C3H10T1/2

  

  1. (College of Engineering, Dali University, Dali, Yunnan 671003, China)
  • Received:2018-08-16 Online:2019-12-15 Published:2019-12-15

Abstract: Focal Adhesion is a multi protein aggregate linked by extracellular matrix and cytoskeleton, forming the pseudopodium for
cell migrations. Microfilaments play an important role in cell adhesion, spreading, movement, endocytosis, cell division and many other
cell functions. This paper studies the cytoskeleton system of C3H10T1/2 cells through analyzing the correlation between Focal
Adhesion and microfilaments and cell areas based on ZEN, ImageJ and SPSS. The results show the significant correlation between the
number of Focal Adhesion and total length of microfilaments, of the area of the plaque and the number of Focal Adhesion, and of the
cell area and the number of focal Adhesion.

Key words: mesenchymal stem cell, cytoskeleton, microfilament, focal adhesion