Objective: To explore the effect of perfusate absorption on PVI in percutaneous nephrolithotomy. Methods: Selected 140
patients who underwent the percutaneous nephrolithotomy according to I-II stage of ASA classification. Based on the amount of the
total fluid volume, they were divided into five groups：the amount of infusion less than 6 000 mL for group A，from 6 000 to 12 000 mL
for group B，from 12 000 to 18 000 mL for group C, from 18 000 to 24 000 mL for group D, and from 24 000 to 30 000 mL for group E.
MAP, HR, airway pressure, PI and PVI were monitored at the end of perfusion, which were compared and analyzed with the indexes
before perfusion. Results: In the operation, MAP, HR and PI values of the patients in five groups had no significant differences before
and after the infusion（P> 0.05）; PVI values had no significant differences before and after the infusion in group A and group B. But in
group C, PVI values were significantly decreasing when perfusion volume was 18 000 mL, and the difference was statistically
significant（P<0.01）; with the increasing of perfusion, the PVI values of group D and group E were lower than those of group C; the
difference was statistically significant（P<0.01）. Airway pressure had significantly increased when perfusion volume was 24 000 mL
compared with group D and group E before infusion, and the difference was statistically significant（P<0.01）. Conclusion: As the
perfusion fluid amount increases, PVI can earlier show the monitoring capacity change after absorbing the perfusate in percutaneous
nephrolithotomy, but there is no significant change in PI.
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