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Table of Content

    15 October 2019, Volume 4 Issue 10
    Fundus Analysis of 239 Cases of Symptomatic Infants Infected with Cytomegalovirus
    SHI Cai-Beng, GE Chi-Chi, LIU Bin, SHU Hui-Hui, LIN Yan-Gong, ZHENG Xiao-Yu, FENG Jia
    2019, 4(10):  1-6.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To investigate the fundus characteristics of infants infected with cytomegalovirus. Methods: The fundus
    characteristics of 239 infants with symptomatic cytomegalovirus infection were retrospectively analyzed. Results: 65 patients had
    moderate to severe fundus abnormalities, 3 of them had pan-retinal chorioretinitis, 12 infants had fundal hemorrhage in one eye or both
    eyes, 49 infants had localized white exudation, and 1 infant both had fundal hemorrhage and localized white exudation. There were 6
    cases with fundal abnormality presented in zone I, 7 cases in zone II, 45 cases in zone III, 2 cases in zone I and II, 2 cases in zone II
    and III, and 3 cases involving the whole retina. Of 20 infants treated with intravenous ganciclovir, 18 infants had complete
    normalization, 2 infants had just subtle pigment epithelial disturbance and retinal lesions. 45 cases were not treated, and 4 cases had
    residual fundus lesions. Conclusion: For infants infected with cytomegalovirus, early screening of the eyes and regular reexamination
    are recommended, especially for infants with low immunity or immune deficiency who have retinochoroiditis should be treated with
    medicine as soon as possible.

    Advances in Etiology and Treatment of Refractory Nocturnal Enuresis in Adolescents
    WEN Jian-Guo, BO Jing-Song
    2019, 4(10):  7-11.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To review the etiological and therapeutical progress of refractory nocturnal enuresis(RNE)in adolescents.
    Methods: Articles on the epidemiology, etiology and treatment of refractory enuresis in adolescents were searched in various
    databases, and then summarized, sorted out and analyzed. Results: The incidence of RNE in adolescents was higher. The causes
    included abnormal bladder function, nocturnal polyuria, sleep and wakefulness disorders, familial inheritance, obstructive airway
    diseases, psychosocial diseases, obesity, bladder and rectal dysfunction, trauma or psychological stress. The treatment can obtain better
    curative effect according to the cause of disease. Conclusion: The incidence of RNE in adolescents is on the rise, and the causes are
    varied. It is necessary to carry out combined treatment according to etiological diagnosis to improve the cure rate of RNE.

    A Case Report of Apert Syndrome and Literature Review
    LI Zhong-Ke, JU Lin, LIANG Beng, DI Xuan
    2019, 4(10):  12-15.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: Through a case report of clinical diagnosis of Apert syndrome, combined with literature study, the diagnosis
    and differential diagnosis of the disease were discussed. Methods: Clinical manifestations, auxiliary examinations and genetic
    diagnosis of the case were analyzed combined with literature. Results: The main clinical manifestations were plump bregma,
    syndactylia deformity and cleft palate. The results of the cranial CT scan showed bilateral lateral ventricle enlargement. The genetic
    testing indicated that there was a heterozygous mutation in exon 7 of the FGFR2 gene in the patient, resulting in the conversion of
    serine encoding the 252th codon of the protein to tryptophan. Conclusion: The FGFR2 gene c.755C>G mutation is the cause of this
    case of Apert syndrome, and genetic analysis can help diagnose. Children with normal head circumference and suspected congenital
    hydrocephalus should be genetically screened and differentiated from Apert syndrome to guide clinical treatment.

    A Case Report of Torsion of the Gallbladder in Pediatric Population and Literature Review
    ZHOU Gao-Xi, SONG Zai, CHEN Gong
    2019, 4(10):  16-18.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To collect gallbladder torsion case data, summarize relevant clinical and auxiliary examination results, and
    improve the accuracy of preoperative diagnosis. Methods: A case of gallbladder torsion in children was reported. The clinical
    manifestations, auxiliary examination images, surgical procedures, and related literature were reviewed retrospectively. Results:
    Gallbladder torsion occurs mostly in elderly women. The incidence of children is extremely low. The course of disease is short, and the
    pain in the gallbladder area is obvious. It may be accompanied by vomiting symptoms, no fever or jaundice. Under the B-ultrasound,
    the "8" shape can be seen in the gallbladder, and the echo at the intersection is high. MRCP can be observed to interrupt the
    gallbladder or the cystic duct is pointed. Very few CTs may see a spiral change in the gallbladder. Conclusion: In children, gallbladder
    torsion is rare, symptoms are confusing, and B-ultrasound and MRCP have important preoperative diagnostic value.

    A Case of Pediatric Calyceal Diverticulum Complicating with Infection
    WU Xiang-Yu, LIU Wei, TUN Rong-De-
    2019, 4(10):  19-21.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To analyze the disease characteristics of calyceal diverticulum in children and introduce the preliminary
    treatment experience of the disease, so as to improve doctors' understanding and diagnosis of the disease. Methods: A case of calyceal
    diverticulum in children admitted to pediatric surgery department of Shandong Provincial Hospital Affiliated to Shangdong University
    was retrospectively analyzed, including gender, age, clinical features, imaging features, treatment process and prognosis. Literature
    review was conducted to summarize the experience of diagnosis and treatment of calyceal diverticulum in children. Results: The patient
    received satisfactory results after surgery, and no recurrence was found in the re-examination 3 months after surgery. Conclusion:
    Calyceal diverticulum is relatively rare. Diagnosis can be made by IVP, retrograde pyelography and CTU in which contrast agent can be
    detected in calyceal diverticulum. Different methods should be selected according to its size, location, infection and stone.

    Influence of the Extracts from Three Astragalus Plants on Platelet Aggregation
    CHEN Lei, CUI Chu-Jun, WANG Min, JIANG Bei
    2019, 4(10):  22-26.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To study the influence of the alcoholic extracts from three Astragalus plants(A. membranaceus, A. ernestii, and
    A. yunnanensis)on platelet aggregation. Methods: After preparation of platelet-containing plasma, different concentrations of the
    extracts of the three Astragalus plants were added to incubate plasma, then their effects on adenosine diphosphate (ADP)or
    arachidonic acid(AA)-induced platelet aggregation, or on the situation without inducer, were observed. Results: Compared with
    solvent control group, all the extracts from the three Astragalus plants significantly inhibited ADP or AA-induced platelet aggregation;
    the inhibitory effects of the extracts from A. membranaceus and A. ernestii on ADP-induced aggregation are better than the extract from
    A. yunnanensis, while the effects of the extracts from A. yunnanensis and A. ernestii on AA-induced aggregation are better than the
    extract from A. membranaceus. The extracts from the three Astragalus plants also could promote normal platelet aggregation.
    Conclusion: All the extracts from three Astragalus plants can inhibit platelet aggregation by different inducer, but their inhibitory
    mechanisms are different.

    The Role of Notch Signaling Pathway in the Regeneration of Peribiliary Vascular Plexus after Ischemia-Reperfusion Injury
    HE Gong-Yang, SU Zi-Ting, SUN Ling, TAN Yun-Bei
    2019, 4(10):  27-31.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To investigate the mechanism of how Notch signaling pathway affect PBVP regeneration after biliary ischemia-
    reperfusion injury. Methods: Male specific pathogen free Sprague-Dawley(SD)rats were used and categorized randomly into three
    groups: the sham operation group(SO), the ischemia reperfusion group(IRI), and the DAPT pretreatment group(DAPT). By
    establishing a rat model of biliary ischemia-reperfusion injury in situ autologous liver transplantation, we analyzed the expression of
    Notch signaling pathway-related protein molecules in the portal area, serum transaminase, and vascular regeneration in the portal area
    (micro-vessel density)after biliary ischemia-reperfusion in rats(microvessel density). Results: Compared with IRI group, the
    expression levels of Notch1 and Hes1 in DAPT 3 d and DAPT 7 d were significantly lower than those in IRI group at the same time
    point; the expression of Dll4 protein in IRI 3 d subgroup was significantly higher than that in DAPT 3 d group. There was no difference
    in Dll4 protein level between IRI 7 d subgroup and DAPT 7 d subgroup. The levels of serum ALT, ALP, GGT and TbiL in DAPT 3 d
    and DAPT 7 d subgroups were significantly higher than those in IRI group at the same time point; The MVD of the portal area DAPT 3
    d, DAPT 7 d was significantly lower than that of the IRI group at the same time point. Conclusion: After biliary ischemia-reperfusion
    injury, the Notch signaling pathway is activated, which promotes the formation of micro-vessels around the biliary tract, and plays an
    important role in the regulation of vascular plexus regeneration around the biliary tract after ischemia-reperfusion injury.

    Study on the Mechanism of Coptidis Rhizoma-Aucklandiae Radix on the Treatment of Ulcerative Colitis Based on Network Pharmacology
    WEN Jian-Xia, LI Yang, HAO Dun-Jie
    2019, 4(10):  32-39.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: Network pharmacology analysis was used to predict the mechanism of Coptidis Rhizoma-Aucklandiae Radix
    in Xianglian Pills in the treatment of ulcerative colitis, and to provide reference for the research of Xianglian Pills. Methods: TCMSP
    database was retrieved by computer to collect the active ingredients and targets of Coptidis Rhizome and Aucklandiae Radix in the
    treatment of ulcerative colitis. Cytoscape 3.7.0 software was used to construct the "component-target-disease" interactions. Finally,
    KEGG pathway enrichment analysis was carried out through DAVID database. Results: 154 active ingredients and 1 248 protein
    targets of Coptidis Rhizome and Aucklandiae Radix were predicted in the treatment of ulcerative colitis. The results showed that
    Coptidis Rhizome and Aucklandiae Radix could play an important role in the treatment of ulcerative colitis by regulating inflammatory
    factors, cell apoptosis and cellular immunity. Conlusion: This study had comprehensively predicted the potential mechanism of
    Coptidis Rhizome-Aucklandiae Radix in the treatment of ulcerative colitis by network pharmacology, which provided theoretical basis
    for clinical application of Coptidis Rhizome-Aucklandiae Radix and even Xianglian Pills in the treatment of ulcerative colitis.

    Study on the Mechanism of Herb Pair "Ephedrae- Cinnamomi" in the Treatment of Colds Based on Network Pharmacology
    ZHANG Le, LI Yang, HAO Dun-Jie
    2019, 4(10):  40-45.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: Taking "Ephedrae-Cinnamomi" as an example, the mechanism of mutual promotion herb pairs was studied by
    using network pharmacology technique. Methods: TCMSP database was used to screen the chemical composition and the targets of
    Ephedrae and Cinnamomi; OMIM database was applied to screen the targets of influenza or cold; PPI database was used to establish
    the interaction between the targets. The "compound-target-disease" complex network diagram was constructed by the Cytoscape
    software. The direct therapeutic targets of Ephedrae and Cinnamomi were screened out, and KEGG and GO pathway enrichment were
    performed by DAVID database. Results: 13 targets and 6 signal pathways in Ephedrae and Cinnamomi were selected, which were
    associated with influenza or cold. Among the targets, Nitric oxide synthase was the important one. The pathways contained HIF- 1
    signaling pathway, Estrogen signaling pathway, Toll-like receptor signaling pathway, etc. Conclusion: The combined administration
    mechanism of Ephedrae and Cinnamomi is predicted by the network pharmacology, which provides a new idea for mutual promotion
    drug pair of Chinese medicine.

    Anti-inflammatory Activity Analysis of Gentiana macrophylla Based on Network Pharmacology
    LI Yang, ZHANG Le, HAO Dun-Jie
    2019, 4(10):  46-51.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: The network pharmacology method was used to predict the targets of the main anti-inflammatory components
    of Gentiana macrophylla. The network relationship of "active components- inflammatory targets- anti- inflammatory pathway" was
    constructed to predict the targets and mechanisms of its intervention in inflammation. Methods: The chemical composition and target
    datasets of Gentiana macrophylla were established by the pharmacological analysis platform of Chinese medicine system; the OMIM
    database was used to screen inflammation-related targets; the PPI database was used to construct protein interaction targets; and the
    "chemical component-functional protein-targets of inflammation" interaction network was constructed using Cytoscape software. The
    key targets for the regulation of inflammation in Gentiana macrophylla were screened out. The KEGG pathway enrichment and GO
    analysis were performed on the selected targets using the DAVID database and Cytoscape plug-in Clue GO. Results: 11 active
    constituents of Gentiana macrophylla were screened and analyzed, including gentianidine, gentianine, gentiatibetine, alpha-amyrin,
    gentianal and loganic acid. 25 anti-inflammatory targets were screened and analyzed, including cell tumor antigen p53, essential
    regulator of NF-kappa-B and tumor necrosis factor receptor-related factors 6 and so on. The possible anti-inflammatory pathways of
    Gentiana macrophylla include apoptosis, TNF signaling pathway, and MAPK signaling pathway. Conclusion: The potential targets of
    Gentiana macrophylla for regulating inflammation were predicted and the mechanism of action was revealed, which provideed reference
    for further study on the anti-inflammatory mechanism and clinical application of Gentiana macrophylla.

    Investigation and Analysis of the Temporary Purchase of Drugs in a Children's Hospital in 2018
    TIAN Jing, LI Quan-Gong, LI Chi, LIU Xiao-Ning, DIAO Chun-Yan, FENG Da-Ying, GUO Pin
    2019, 4(10):  52-55.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To investigate the temporary purchase of drugs in a children's hospital, and to provide reference for promoting
    the standardized management of temporary purchases of drugs and rational use of drugs. Methods: Analyze the relevant regulations for
    the temporary purchase of drugs in a hospital, and retrospectively investigate the temporary purchase of drugs from January to
    December 2018 in a children's hospital. Results: Departments subscribed for drugs were mainly the Department of Hematology,
    Cardiology, PICU, Oncology, and Nutrition. The drugs purchased were mainly anti- tumor drugs, antibacterial drugs, parenteral
    nutrition and electrolyte replenishing liquids, external medicines, and immunosuppressants. Conclusion: There were unreasonable
    purchases of drugs in the hospital. It is necessary to continuously improve the management of temporary purchase of drugs and promote
    the rational use of drugs

    Application of Inquiry Teaching in the Practice of Pharmacognosy Teaching
    ZHANG De-Quan, YANG Ru-E, WANG Shuang
    2019, 4(10):  56-59.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To explore a new method on improving the teaching quality of pharmacognosy. Methods: Inquiry teaching was
    carried out among students studying Pharmacy. Meanwhile, a questionnaire survey was used to analyze and assess the teaching quality.
    Results: Most of the students(82.35%)were satisfied with the teaching practice. They made obvious progress in searching references,
    making courseware, classroom teaching practice and classroom discussion; however, there was no obvious difference on test scores
    compared to previous years. Conclusion: Inquiry teaching could improve teaching quality of pharmacognosy and it should be adopted
    in teaching process of colleges and universities.

    Analysis of the Epidemiological and Clinical Characteristics of 42 Cases of Scrub Typhus
    MAO Hua-Hui, HUANG Jian-Mei, ZHANG Shao-Min, LIU Min, MA Hai-Jiang, DIAO Mo-Run
    2019, 4(10):  60-62.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To investigate the epidemiological and clinical characteristics of 42 cases of Scrub typhus, and to propose
    effective measures of its prevention, diagnosis and treatment. Methods: The data of 42 patients diagnosed with Scrub typhus was
    analyzed retrospectively. Results: 42 patients were distributed in 9 towns, and the incidence peak was from June to September. Of all
    the patients, 18(42.86%)were male and 24(57.14%)were female. The average age was(58.95±15.05)years, and all patients were
    from rural areas. Fever occurred in all cases. 35 patients(83.33%)showed typical scab or ulcer. Eosinophils were decreased in 27
    cases(64.29%), liver function was impaired in 33 cases(78.57%), heart function was impaired in 31 cases(73.81%), and lung
    function was impaired in 12 cases(28.57%). All the 42 cases(100%)were cured clinically. Conclusion: Scrub typhus has obvious
    seasonality, and its clinical manifestations are complex and diverse, involving multiple organs. Acute fever is the first symptom, scab or
    ulcer is the characteristic diagnostic clue, and doxycycline treatment has good effect.

    Epidemiological Characteristics and Clinical Analysis of 87 Cases of Newly Diagnosed Pulmonary Tuberculosis in Yongsheng County of Yunnan Province
    WANG Song-Ju, MAO Hua-Hui, HUANG Jian-Mei, ZHANG Shao-Min, LIU Yan, DIAO Mo-Run
    2019, 4(10):  63-66.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To analyze the epidemiological and clinical characteristics of active tuberculosis in rural areas. Methods: The
    epidemiological and clinical data of 87 patients with newly diagnosed pulmonary tuberculosis from May 2017 to January 2018 were
    collected. Results: 87 patients were from rural areas, among whom 85(97.7%)were farmers, and 2(2.3%)were retired. The minority
    patients accounted for 67.8% of the total, male : female = 1.6 : 1. The average age was(50.9±16.3)years old. The sputum smears were
    found to be negative in 47 cases(54.0%)and positive in 40 cases(46.0%). Conclusion: Active tuberculosis in this region has the
    characteristics of ethnic minorities, rural population, middle-aged and elderly, males, and malnutrition patients. The rural minority
    areas in western China are still the key areas for tuberculosis prevention and control.

    Clinical Characteristics of 64 Adult Patients with Epstein-Barr Virus Infection
    SHI Rong-Jie, CHEN Chun-Man, TAO Qiu-Yan, LUO Mei-Hua
    2019, 4(10):  67-70.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To investigate the clinical characteristics of Epstein-Barr virus(EBV)infection in adults, and to provide
    scientific basis for early diagnosis and treatment of EBV-related disease. Methods: Clinical data, laboratory examinations, treatments
    and follow-up results of 64 adult patients with EBV infection were retrospectively analyzed. Results: The clinical manifestations of
    EBV infection in adults were complex and varied. The main manifestations were abnormal liver function, fever, burnout, fatigue,
    headache, myalgia, low back pain and other toxemic symptoms. Conclusion: Most patients with EBV infection in adults have good
    prognoses, and a small number of patients have prolonged illness. For adult patients with long-term fever due to unexplained liver
    damage, EBV related diseases should be carefully examined.

    Research Progress on Cardiovascular Disease in Trans-Plateau Regions
    TUN Xin-Hua, CHEN Zhang-Rong, LIU Hong, LI Zhen-Feng, YANG Bin
    2019, 4(10):  71-74.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To understand the characteristics of cardiovascular disease in the region from the trans-sub-plateau to the
    plateau. Methods: Study the literature and review the recent papers on cardiovascular disease in this region. Results: Trans-plateau
    regions refers to the areas cross sub-plateau to plateau area(altitude about 1 000-3 500 m). Cardio-vascular diseases have different
    characteristics and mechanism in these regions. There are few studies that specifically address cardiovascular disease across the trans-
    plateau regions. Conclusion: There are few studies on cardiovascular diseases across the plateau at an altitude of 1 000-3 500 m,
    without systematic studies, and the pathophysiological mechanism is still unclear. This paper proposes the concept of trans-plateau
    cardiovascular disease and conducts in-depth research, which is of great significance for the prevention and treatment of cardiovascular
    disease in people with short-term exposure or long-term living in trans-plateau area.

    Clinical Study on the Treatment of Malignant Ascites with Percutaneous Indwelling Central Venous Catheter Combined with Ozonated Water Perfusion Drainage
    FU Hai-Yan, LUO Yu, LI Gong-Juan, XUE Lian, ZHANG Ji, LI Hai-Wen
    2019, 4(10):  75-78.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To observe the clinical effects of percutaneous indwelling central venous catheter combined with ozonated
    water perfusion drainage on malignant ascites and its impact on patients' quality of life. Methods: 92 cases of malignant ascites in the
    department of oncology care in the Sixth Affiliated Hospital of Dali University were chosen as the research objects and were randomly
    divided into two groups. The experimental group was given percutaneous indwelling central venous catheter combined with peritoneal
    perfusion with ozonated water, and the control group was given percutaneous indwelling central venous catheter drainage ascites. The
    treatment effects and the improvement of life quality of the two groups were evaluated and compared. Results: The total effective rate of
    the experimental group was 59.2%, and that of the control group was 41.9%, the difference was statistically significant between two
    groups(P=0.045<0.05). According to EORTC QLQ-C30 grade, the tired scores, dyspnea scores, sleepless scores of the experimental
    group were all lower than those of the control group and the differences were statistically significant between two groups(P<0.05). The
    median survival time in the experimental group was 2.8 months, while that in the control group was 2.1 months. Conclusion:
    Percutaneous indwelling central venous catheter combined with ozonated water perfusion drainage can improve the quality of life in
    late stage malignant tumor patients and also prolong overall survival to some degree.

    Unilateral Parotid Warthin Tumor in 5 cases and Literature Review
    JIAN Jiang-Gong, DAI Hua-Zhong
    2019, 4(10):  79-81.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To study the diagnosis and treatment of parotid Warthin tumor. Methods: The clinical data of 5 cases of
    Warthin tumors admitted to the Second Affiliated Hospital of Dali University from May 2016 to January 2018 were retrospectively
    analyzed. Results: 5 middle-aged and elderly patients were treated with unilateral painless earlobe mass as the first symptom. All of
    them were male patients with at least 20 years of smoking history. All cases were diagnosed by massectomy. Conclusion: Correct and
    comprehensive understanding of Warthin tumor is mainly based on biopsy diagnosis. The main treatment methods are surgical removal
    of the tumor, preservation of the parotid gland function, and reduction of postoperative complications and recurrence.

    Analysis of Operation Effects on 24 Cases with Eyelid Malignant Tumor
    DIAO Hui-Qiong
    2019, 4(10):  82-85.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To explore the methods and effects of eyelid malignant tumor resection and eyelid defect repair. Methods: The
    complete medical records of 24 patients were retrospectively analyzed, the recurrence of the tumors and the recovery of eyelid functions
    were followed up, and therapeutic effects of resection of controlled eyelid malignant tumor and repair of eyelid defects were analyzed.
    Results: Except for one 82-year-old patient who died of pulmonary infection after 1 year of follow-up, the other patients were followed
    up for 2 to 7 years, with recurrences of 1 case in 3 years and 1 case in 5 years. All the other cases did not relapse, with no deformity in
    appearance and complete closure of palpebral fissure. Conclusion: Only standard eyelid mass resection can lead to perfect eyelid
    defect repair, and Mohs resection is the preferred method to ensure the cleanness of tumor resection. The repair of eyelid defect needs
    personalized design to achieve the harmonious unity of function and appearance.

    Clinical Observation on the Treatment of 90 Cases of Stroke with Acupuncture Method
    TUN De-Hai
    2019, 4(10):  86-87.  DOI: R255.2
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    Objective: To observe the clinical efficacy of acupuncture in the treatment of functional recovery in patients with stroke.
    Methods: 90 patients with stroke were treated with acupuncture. The main acupoints were Shuigou, Neiguan, Sanyinjiao, and Baihui,
    etc. Auxiliary acupoints were Hegu, Zusanli, Weizhong, and Jiquan, etc. Results: The effective rate of acupuncture for limb stroke
    dysfunction is 86.67%. Conclusion: Acupuncture is effective in the treatment of limb dysfunction in stroke.

    Prevalence and Risk Factors of Metabolic Syndrome among Urban Residents of Zhaotong City
    TUN Min-Song, ZHOU Fu, YIN Chao-Lan
    2019, 4(10):  88-91.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective:In order to understand the prevalence and related risk factors of metabolic syndrome(MS)among urban
    residents of Zhaotong City, and to provide references for the prevention and treatment of MS. Methods: People taking physical
    examination in the hospitals were selected as the research objects, and the required data were collected to statistically analyze the
    prevalence and related risk factors of MS. Results: The overall prevalence of MS was 9.99%. 13.37% for males and 5.14% for females,
    and the difference was statistically significant (P<0.05). The proportion of dyslipidemia was the highest(45.01%)among the research
    object. The combination of overweight and/or obesity, hypertension, and dyslipidemia was the highest in the expression of MS, which
    was 40.11%. Except urea, other factors including gender, age, body mass index, systolic blood pressure, diastolic blood pressure, blood
    glucose, triglycerides, high-density lipoprotein, low-density lipoprotein, uric acid, and MS prevalence differences all had statistic
    significance(P<0.05). Multivariate Logistic regression analysis showed that male, age, LDL, and uric acid were risk factors for MS.
    Conclusion: Although the prevalence of metabolic syndrome in urban residents of Zhaotong City is relatively low, it is still necessary to
    actively control various risk factors through screening in the early stages and formulating targeted and individualized measures so as to
    improve patients' quality of life.

    Status Quo, Problems and Countermeasures of the Clinical Practice of MBBS International Students from South Asia in Dali University
    DIAO Shan-He, YANG Lin, LI Cai-Dui, LI Li-Hua, YANG Ge-Hun, ZHANG Yuan-Yuan-
    2019, 4(10):  92-95.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To study the problems and difficulties in clinical practice teaching for South Asian medical students in the
    Affiliated Hospital of Dali University, and put forward feasible countermeasures to improve the quality of clinical practice for South
    Asian medical students. Methods: Questionnaires and interviews were conducted for 81 foreign medical students who were from grade
    2013 of Dali University and were studying in the Affiliated Hospital, and 66 teachers who undertook teaching tasks for foreign medical
    students. Results: The overall Chinese proficiency of foreign students in the Affiliated Hospital of Dali University was not good, the
    quality of clinical practice needed to be improved, and the overall foreign language proficiency of the teaching staff needed to be further
    strengthened. Conclusion: Combining with the practice of South Asian medical students' education in Dali University, we can improve
    the quality of clinical practice of foreign medical students by strengthening their Chinese teaching and teachers' foreign language
    training, so as to adapt to the development of international education of foreign medical students.

    Application Value of Humanized Nursing in Surgery Rooms
    WANG Jian-Ping
    2019, 4(10):  96-97.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To explore the application value of humanized nursing in surgery rooms. Methods: 80 patients with surgical
    procedures from October 2017 to October 2018 in People's Hospital of Ruili City were randomly divided into the control group and the
    experimental group, with 40 cases in each group. The control group received routine nursing and the experimental group received
    humanized nursing. The nursing satisfaction of the two groups of patients was compared and analyzed by relevant statistical methods.
    Results: The nursing satisfaction of the experimental group was significantly higher than that of the control group. Conclusion:
    Humanized nursing has a good application value in the surgery room and is worthy of clinical application.

    Nursing Care of 3 Patients with Median Nerve Injury Caused by Percutaneous Brachial Artery Puncture
    DIAO Yan, NI Yan, BIAN Li-Yan, YANG Weng-Bo
    2019, 4(10):  98-100.  DOI: 10. 3969 / j. issn. 2096-2266.
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    Objective: To summarize the nursing care of patients with median nerve injury caused by percutaneous brachial artery
    puncture. Methods: The nursing experience of 3 patients with median nerve injury caused by percutaneous brachial artery puncture
    was analyzed. Results: Operations for all the patients were successful, median nerve was released and the tactile sensation of finger
    pulp pain was basically recovered. However, the flexion of thumb and index fingers was not recovered. Conclusion: After the nursing,
    the main symptoms of median nerve injury were basically eliminated. The nursing experience of this paper was worthy of clinical
    application due to the satisfying results.