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大理大学学报
月刊,1980年创刊
主管:
云南省教育厅
主办:
大理大学
地址:
云南省大理市古城弘圣路2号
大理大学学报编辑部
邮编:
671003
电话:
0872-2219939,
0872-2219133 (社会科学类)
0872-2219938 (医学类)
0872-2218160 (理工类)
Email:
dldxxuebao@163.com
ISSN:
2096-2266
CN:
53-1232/Z
Volumn Content
Journal of Dali University 2024 Vol.9
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Experience Generation from the Healthy China Strategy and Chinese Modernization:#br# A Case Study of Dali City#br#
Yuan Lei, Yang Yanchi
Journal of Dali University 2024, 9 (
1
): 1-7. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 001
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45
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Under the leadership of the Chinese Communist Party, the Chinese nation has established and developed the people′s
healthcare industry. In the grand practice of health governance, unique Chinese experiences, treasures, and miracles have emerged,further strengthening confidence and initiative in promoting the Chinese modernization of the healthcare industry. In pursuing the path of Chinese modernization, it is essential to adhere to the principle of prioritizing people′s health and promoting healthy development,maintain a problem-oriented and goal-guided approach, and uphold integrity and innovation to effectively address the overall and longterm issues affecting public health. To modernize the health and wellness industry through Chinese modernization, it is necessary to refine health promotion policies and better meet the growing health and wellness needs of the public. Dali City′s efforts in creating a world-class tourism and healthy living destination, achieving the status of a National Healthy City, establishing a Provincial-level Chronic Disease Prevention and Control Demonstration Zone, and forming an integrated medical and health community are all part of the "Healthy Dali" initiative. These achievements and experiences serve as a microcosm of Healthy China′s development, as well as beneficial practices and explorations of Chinese modernization, which deserve further study and serve as useful references.
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Innovation in the Path of Joint Construction and Co-Construction for Party Construction in the Same
#br#
Type and Area of State-Owned Enterprises: "12345" Model as an Example
Chen Huairui, Li Qianfu, Li Mei
Journal of Dali University 2024, 9 (
1
): 8-14. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 002
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The Joint Construction and Co-construction for Party construction is an important way for socialism with Chinese characteristics to enter the new era and state-owned enterprises to strengthen the Party building. The implementation of Joint Construction and Co-Construction for Party construction work can consolidate the important position of state-owned enterprises of the same type in the same river basin in the national economic and social development, break the interest barriers to promote their healthy development, practice the people-centered idea to serve local development, and integrate resource advantages for better serving rural revitalization. At present, there are five main modes of Joint Construction and Co-Construction for Party construction in the stateowned enterprises of the same type and in the same areas, i.e., Party building with the masses, regional co-construction, project-based co-construction, group companies co-construction mode and point-to-point co-construction. Each of them has its own advantages and disadvantages. On the basis of summarizing the experience of party building of these state-owned enterprises, Yunnan Company and Jinshang Company established the "12345" model and path exploration. Its ideas, goals, modes and paths are of great innovative value, which provides beneficial reference for other state-owned enterprises.
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On Conversation Analysis of Aphasia Based on Daily Interaction
Yang Shiqiao, Zhang Fang
Journal of Dali University 2024, 9 (
1
): 15-20. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 003
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Aphasia affects patients′ conversational communication, interpersonal communication and interpersonal relations, and thus
affects their family and social life. The study of conversation analysis in aphasia is divided into six steps: preparation, conversation
recording, transcription, conversation assessment, the process from conversation assessment to conversation training and conversation training. This paper makes a conversation analysis of aphasia, investigates the influence of aphasia on the interaction of patients, and evaluates the three main areas of conversation including trouble and repair, turns and sequences, topic and overall conversation. And it inspects patients how to adapt to aphasia and the problems it may cause in conversation. Based on that, it aims to develop a new way of interaction that works well for them, and form an individualized program of conversation training, helping aphasiac return and adapt to their family and social life.
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Connotation, Manifestation and Experiential Enlightenment of the Historical Initiative of the CPC
Li Xiangxiang , Xu Ye , Sun Zhaojing
Journal of Dali University 2024, 9 (
1
): 21-27. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 004
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From the perspective of historical materialism, the historical initiative of the CPC is the ability and spiritual character of
actively creating history formed under the guidance of scientific theory, long-term practice and experience, and active responsibility. Due to the richness of social practice in different periods, it presents a variety of specific forms. In the theoretical form, it represents three leaps to realize the modernization of Marxism in China. In the practical form, it represents great achievements in all-round historical development. In the spiritual form, it represents the construction of the spiritual pedigree of the CPC. In the empirical form, it represents the formation of three important historical resolutions in the history of the CPC. Taking history as a mirror, we should adhere to the leadership of the Party, strengthen the core consciousness, master the ability of the Marxism, strengthen the noble faith, rely on the people, stimulate the initiative, summarize historical experience and draw wisdom, thus continuing to carry forward the historical initiative and take the road to the new era.
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Engels' Thoughts on the Socialization of Housework and Its Realistic Enlightenment
Wu Yuxing, Zhang Xinru
Journal of Dali University 2024, 9 (
1
): 28-33. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 005
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In the new era, China′s aging problem and the implementation of the three-child policy are bound to increase women′s
housework. Therefore, it is urgent to promote the socialization of housework. Engels′ thought on housework socialization is helpful to guide and promote the high-quality development of housework socialization. Its basic connotation is embodied as follows: to exert women′s subjectivity, to be practical in the objective world, and to be scientific rooted in historical materialism. Its internal purpose is embodied in the direct demand of promoting women′s direct liberation, the ideal pursuit of concluding love and marriage, the fundamental requirement of promoting production development, and the inevitable requirement of people′s all-round development. Its inspiration for promoting the socialization of housework lies in: consolidating the material foundation, adhering to new idea that the new development concept leads the high-quality development of productivity, strengthening scientific and technological empowerment and modernization support with digital technology, giving full play to the advantages of the system, and enhancing public services and its security system.
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Atheism is the Traditional Cultural Basis for the Harmonious Coexistence of Various Religions in China
Rong Chuan
Journal of Dali University 2024, 9 (
1
): 34-39. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 006
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Atheism is the ideological background of Chinese culture and the important ideological basis for the integration of Marxism
and Chinese culture. History has proved that all religions in China are influenced, cultivated and guided by the atheist ideology of
Chinese culture, which is manifested as the integration of core ideas and spiritual cultivation, and the integration of loyalty and filial
piety ethics on the external level. Therefore, it can be said that atheism is an important ideological basis for the harmonious coexistence of all religions in our country, and an important ideological and theoretical guarantee for the healthy inheritance of religions in China at present.
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Exploration of the Intrinsic Logic and Path of Solidly Promoting Common Prosperity in the New Era
#br#
from the Perspective of Allocation
Wan Hongxia
Journal of Dali University 2024, 9 (
1
): 40-45. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 007
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After the comprehensive establishment of a moderately prosperous society, solidly promoting common prosperity has
become an important goal of the new historical stage. Solidly promoting common prosperity requires not only promoting high-quality economic development but also ensuring proper income distribution. Currently, compared with the goal of common prosperity, there are still lots of problems in the field of income distribution in China, including a large gap in initial income distribution, insufficient adjustment in redistribution, and inadequate driving force in tertiary distribution. In order to solidly promote common prosperity, it is necessary to establish an initial distribution system that balances efficiency and fairness, and increase the proportion of labor compensation in the initial distribution. It is also important to improve the degree and precision of adjustment in redistribution through taxation, social security, and transfer payments, and ensure that the benefits of development are enjoyed by all residents. Furthermore, the tertiary distribution should play a crucial role in promoting common prosperity by establishing a system and mechanism that primarily relies on incentives, and creating a favorable social atmosphere where the rich help the poor.
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Research on the Path of Social Work Intervention in Public Health Crisis
Gu Yao, Peng Huamin, Guo Jianhong
Journal of Dali University 2024, 9 (
1
): 46-52. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 008
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It is of great significance to explore ways for social work to intervene in emergent public health crises to promote all parties
to participate in the national emergency rescue system. Based on crisis intervention theory and ecosystem theory, in-depth interviews were conducted with the staff of Social Work Association of J Province and the coordinators of all parties. The study found that the Social Work Association of J Province mobilized resources from all sides to assist the country in jointly fighting the epidemic, and its organization and action mode were efficient and practical. However, the intervention path of social work was still insufficient, and it needed to further improve the existing problems from micro, meso and macro perspectives.
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On Compulsory Licensing of Clean Energy Technology under the Background of Carbon Peaking and
#br#
Carbon Neutrality
Ma Zhongfa, Zhao Hexiang
Journal of Dali University 2024, 9 (
1
): 53-63. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 009
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When China joined the Paris Agreement, it proposed to strive to achieve carbon peaking in 2030 and carbon neutrality in
2060. Under the background of dual-carbon, some scholars proposed to implement compulsory licensing of clean energy technology by comparing compulsory licensing of medicines. However, the existing theory has a logic of argumentation fallacy, a lack of dimension and many other problems. Through the external justification of legal philosophy based on environmental rights, the internal justification of jurisprudence based on legal norms, the empirical analysis based on the implementation of clean energy patents, and the comparative analysis based on clean energy patents and pharmaceutical patents. It is concluded that clean energy compulsory licensing has legally justified, but not practically necessary. Even so, the compulsory licensing system should be improved to play an assistant role in technology transfer negotiations, promote the transfer of clean energy technology, and guarantee the long-term goals of carbon peaking and carbon neutrality.
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On the Implementation Path of Sustainable Development Principle in International Law
Zhao Jianfu
Journal of Dali University 2024, 9 (
1
): 64-74. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 010
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The principle of sustainable development has developed into a principle of international law for mankind to cope with global
challenges, but it faces various difficulties and challenges in the process of implementation. The fragmentation and softening of
international law norms in the field of sustainable development, and the rise of non-state actors have had a significant impact on the understanding and implementation of sustainable development principle. Through the systematization of international law on sustainable development and the updating of implementation theories and methods, it is necessary to improve the system of rules applicable to the principle of sustainable development, give play to the constructive role of non-state actors, and enhance the binding force and enforcement of the principle of sustainable development through international economic and trade treaties and dispute settlement mechanisms, so that the principle of sustainable development can be correctly implemented and enforced in international law.
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Optimization of Cultivation Path for Full-Time Master of Education in Dali University
Zhuang Yukun, Li Na
Journal of Dali University 2024, 9 (
1
): 75-80. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 011
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Dali University full-time Master of Education cultivation has maintained a high proportion of non-normal graduates among
candidates; the barriers to promoting the partnership between universities and primary and secondary schools still exist; the bridge effect of teacher-educators who train full-time master of education in communication between educational theory and educational practice needs to be strengthened; the contradiction between academic and practical aspects remains unsolved in the classroom teaching reform of full-time M.Ed. Thus, we need to encourage universities′ academic research to nurture teaching practice in primary and secondary schools, and we need to implement mutually beneficial and win-win cooperation between both sides. It is also necessary to establish the teacher educator cultivation mechanism and promote its coordination with the dual tutorship system. Moreover, we need to reform M.Ed. practical teaching with the concepts of reflective practice ability cultivation.
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System Construction of Ideological and Political Education in Social Work Major:
#br#
Concept, Content and Practice
Li Jiongbiao
Journal of Dali University 2024, 9 (
1
): 81-88. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 012
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Ideological and political education in curriculum emphasizes the spreading, practicing and reproducing of social
mainstream thoughts. Social work is a value-oriented practical major, in which value spread, value practice and production are
highlighted in professional education. It is rich in education quality and superior resources featuring in ideological and political
education. For the value concept, it embodies the implication of ideological and political education which attaches equal importance to both sociality and individuality. For the content, it has the significance of national political education, social moral education, individual life education and other meanings. For the practice path, it focuses on the field of daily life, and promotes the spiral development of service learning and reflective practice through the practice model of service learning. The system of ideological and political education in social work major curriculum has realized the integration of ideas, content and practice, which can continuously enhance the reality and effectiveness of ideological and political courses, and promote the comprehensive and subjective development of ideological and political education.
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A Study on the Current Situation of College English Classroom Ecology in Local Universities
#br#
from the Perspective of Educational Ecology: Dali University as an Example
Wu Huijuan, Yang Qinyan, Xiao Yangtian
Journal of Dali University 2024, 9 (
1
): 89-96. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 013
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24
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By means of questionnaire surveys, semi-structured interviews and classroom observation, the current situation of college
English classroom ecology has been investigated and studied from the perspective of educational ecology. It is found that the current college English classroom ecology is imbalanced. On the basis of analyzing the causes of the ecological imbalance of college English classroom, five suggestions are proposed to optimize college English classroom ecology with the aims of enriching the empirical research of college English classroom teaching in local universities and providing references for the following researchers.
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A Comparative Study on the Influencing Factors of Online Chinese Learners' Demotivation:
#br#
Two Universities in Yunnan Province as an Example
Peng Xiaojuan, Xu Ningyang, Chen Sirong
Journal of Dali University 2024, 9 (
1
): 97-104. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 014
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Taking 287 online Chinese learners from universities A and B in Yunnan Province as the research objects, this paper
adopts quantitative and qualitative research methods, factor analysis, descriptive statistical analysis, analysis of variance and other
means to explore the main influencing factors of online Chinese learners′ demotivation. The results verified that network class, teacher, courses and self are the factors that lead to the decline of learning motivation of Chinese learners in the universities A and B in Yunnan province. There are obvious differences in demotivation factors among learners of different language proficiency, different universities and different districts based on research results. Finally, specific suggestions are given to promote learning motivation of learners in two universities.
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Progress and Trends of Language Processability Theory in the Study of Second Language
#br#
Acquisition Sequence
Cao Yanting, Li Chunlin, Bo Wei
Journal of Dali University 2024, 9 (
1
): 105-111. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 015
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19
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Processability Theory (PT) defines the level of second language development from the perspective of cognitive processing.
It is closely related to the learning environment, acquisition order, acquisition criteria and first language transfer, and has become one of the most important theories of second language acquisition. To some extent, the development of the theory of language processing represents the trend of the study of acquisition order. Based on the basic concepts and theoretical framework of Processability Theory, this paper further reviews the empirical studies on the theory and learning environment, acquisition order, language typology and other factors, so as to explores the unity and divergence between the level of language processing and the order of second language acquisition in terms of syntactic units, language types and interlanguage systems. Finally, this paper summarizes the development characteristics of the theory in the study of second language acquisition and puts forward the development trend of the theory in the study of second language acquisition sequence.
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Research on Development Path and Countermeasures of E-commerce Livestreaming Industry:
#br#
Dalian City as an Example
Wen Tao, Wang Jihua
Journal of Dali University 2024, 9 (
1
): 112-119. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 016
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With its own unique advantages, e-commerce livestreaming has created a new shopping model, bringing new
breakthroughs for the upgrading of the traditional supply chain, thus greatly shortening the distance between products and customers, finally it becomes a new form of economic growth. Affected by the COVID-19 epidemic, the traditional sales methods have made the special products in Dalian unsalable, and the economic development has been seriously affected. When the advantages of e-commerce livestreaming began to emerge, Dalian city seized the opportunity to vigorously develop the e-commerce livestreaming industry, hoping to stimulate people′s consumption desire and boost the economy. This paper summarizes the development status of Dalian′s ecommerce livestreaming industry after the outbreak of the epidemic, analyzes the opportunities and challenges, and puts forward strategies for its future development.
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On Contemporary Youth "Hybrid Entrepreneurship": A Review of Its Academic History and Prospects
Cao Xing
Journal of Dali University 2024, 9 (
1
): 120-128. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 01. 017
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With the emergence of a large number of "slash" youth around the world, those who hold both the identity of "employed"
and "self-employed", as typical representatives of hybrid entrepreneurs, have begun to receive wide attention. As a new research field
driven by practice, domestic research on this issue is not mature enough. This study reviews the relevant literature of "hybrid
entrepreneurship" in at home and abroad, clarifies the connotation and classification, and systematically analyzes the antecedents,
subsequent choices and influences of "hybrid entrepreneurship". On this basis, the limitations of existing research are summarized and
the future research direction is prospected.
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Chain Chemical Constituents of Malus rockii#br#
Liu Yijun, , , Yang Li, , , Lang Lijuan, , Bai Huirong, , , Jiang Bei, , , Xiao Chaojiang, ,
Journal of Dali University 2024, 9 (
2
): 1-3.
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Objective: To study the chemical constituents of the dried twigs and leaves of Malus rockii. Methods: Silica gel, MCI, and
Sephadex LH-20 column chromatography were used to isolate and purify the chemical constituents from the 95% ethanol extract of the
dried twigs and leaves of M. rockii. The isolated compounds were identified based on physicochemical properties and modern
spectroscopic analysis techniques. Results: Seven monomeric compounds were isolated from the 95% ethanol extract of the dried twigs
and leaves of M. rockii and were identified as trans-phytol (1), phytenal (2), phytyl palmitate (3), 1-hexadecanoyl propan-2, 3-diol
(4), methyl 9, 12, 13-trihydroxyoctadeca-10E, 15Z-dienoate (5), α-linolenic acid (6), and octadecanol (7). Conclusion: All the
compounds were isolated from M. rockii for the first time, and compounds 1-6 were isolated from the Malus genus for the first time.
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Study on Extraction and Inclusion Processes of Volatile Oil from Fuzheng Pixie Granules
Luo Qun, Ren Guilin, Pu Qingrong, Ren Wei, Wang Raoqiong, Liang Pan, Yang Sijin
Journal of Dali University 2024, 9 (
2
): 4-7.
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15
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Objective: To optimize the extraction and inclusion process of volatile oil from Fuzheng Pixie granules. Methods: L9(34)
orthogonal design experiment was used to optimize the extraction process of volatile oil, with the oil yield as the index. The inclusion
process of volatile oil with β-cyclodextrin was optimized with the yield of inclusion complex and the inclusion rate of volatile oil as the
indexes. Results: The optimal extraction process of volatile oil was soaking in 10 times the amount of water for 0.5 hours, followed by
extraction for 4.5 hours. The average oil yield of volatile oil in three verification tests was (0.91±0.01)%. The optimal inclusion process
of volatile oil was a ratio of β-cyclodextrin to volatile oil of 10:1, inclusion temperature of 40 ℃, and inclusion time of 3 hours. The
average yield of inclusion complex in three verification tests was (84.48±0.75)%, and the average inclusion rate of volatile oil was
(90.69±0.79)% . Conclusion: The optimal extraction process and the optimal inclusion process of volatile oil of Fuzheng Pixie
granules are reasonable in design and stable in results, which are suitable for industrial production.
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Analysis of the Usage of National Essential Medicines in a Township Health Center in a Border County of Yunnan Province from 2018 to 2021
Zhang Ting, Lei Jiajia, Xu Lei, Yang Xiaoli
Journal of Dali University 2024, 9 (
2
): 8-13.
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Objective: To investigate the usage of national essential medicines in a township health center in a border county of
Yunnan Province from 2018 to 2021. Methods: The types, names, dosage forms, sales amounts, and usage of national essential
medicines in the health center from 2018 to 2021 were statistically analyzed, ranked, and the affordability of the top 20 national
essential medicines in sales was evaluated. Results: From 2018 to 2021, the types of national essential medicines used in the health
center and the sales amount increased year by year, and the proportion of the number of national essential medicine varieties to the total
number of medicine varieties in the health center was 67.57%, 72.42%, 73.97%, and 76.63% respectively, while the proportion of sales
amount to the total sales of medicines in the health center was 63.86%, 65.84%, 66.15%, and 70.23% respectively. The affordability of
the top 20 national essential medicines in sales selected was good, and it improved year by year. In terms of rational use of national
essential medicines, the proportion of irrational prescriptions was 17.62%. Conclusion: The implementation of the national essential
medicine system in the health center is relatively good, but there is still a certain gap compared with the requirements of the health
administrative department, and it is necessary to further strengthen the equipment and rational use of national essential medicines.
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Reform and Practice of Open Experiment Teaching Mode of Inorganic Chemistry in Medical Majors
Hao Fangfang, Lan Hai, Liu Xi, Hu Kan
Journal of Dali University 2024, 9 (
2
): 14-19.
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The open experiment of inorganic chemistry is the improvement and extension of the traditional experiment of inorganic
chemistry, and it is also an effective means to stimulate students' innovative thinking and cultivate their innovative ability. Due to the
different teaching objectives of each school, the open experiment teaching mode of inorganic chemistry is also different. This research
discusses the reform and practice of the open experiment teaching mode of inorganic chemistry in medical majors in order to meet the
needs of training innovative talents.
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Reform and Exploration of Pharmacokinetics Teaching Combining Competence-Based and Ideological and Political Education in Courses
Liu Xi, Lai Yong, Zhou Ping, Liu Heng, Wang Yan
Journal of Dali University 2024, 9 (
2
): 20-23.
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13
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With the development of pharmacokinetics discipline both domestically and internationally, new techniques and theories
emerge endlessly. Starting from the reform and construction of teaching curriculum, this study presents the latest and cutting-edge
information of the curriculum to students, broadens their horizons, and constructs a pharmacokinetic mixed teaching concept and
teaching model based on "case analysis + flipped classroom". By adopting diversified teaching methods such as heuristic teaching,
inquiry teaching, critical and speculative teaching and so on, as well as the combination of case teaching and problem guidance, the
combination of lecturing and "flipped classroom" and other diverse teaching forms, the roles of "teacher" and "student" can be exchanged
to improve the innovation, cutting-edge, epochal and challenging degree of this course, and cultivate students' comprehensive ability and
advanced thinking to solve complex problems. And then enhance the curriculum connotation, build a high-level curriculum system, and
develop unique training characteristics.
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Effects of Intestinal Flora and Serum Metabolites on Visceral Sensitivity in Post-Infection Irritable Bowel Syndrome
Yan Bo, Pan Ying, Tian Pingping
Journal of Dali University 2024, 9 (
2
): 24-31.
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Objective:To investigate the changes of intestinal flora and serum metabolites in mice with post-infection irritable bowel
syndrome (PI-IBS), and analyze the effects on visceral sensitivity. Methods:The PI-IBS model was prepared by Trichinella spiralis
infection method, and the intestinal microbial changes of PI-IBS mice and normal mice were analyzed by 16S rDNA sequencing. The
changes of serum metabolites were analyzed by serum metabolomics. Spearman's correlation analysis was used to analyze the
correlation between different metabolites and different flora in the two groups. Results:The results of 16S rDNA sequencing showed
that mouse gut metagenome and g_Alistipes were the critical gut microbes in PI-IBS mice. A total of 22 intergroup differential
metabolites were identified by metabolomics analysis, involving 16 metabolic pathways, mainly including biosynthesis of amino acids,
cysteine and methionine metabolism, arginine biosynthesis, synaptic vesicle cycle and other pathways. Conclusion:Changes in
intestinal flora and serum metabolites are involved in the production of visceral hypersensitivity to PI-IBS.
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Effects of Mycobacterium tuberculosis EsxV/W Fusion Protein on the Phenotype of Mycolicibacterium smegmatis and Macrophage Function
Yu Haiyan, Li Yujie, Ren Qin, Yang Guoping
Journal of Dali University 2024, 9 (
2
): 32-38.
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Objective:To construct recombinant Mycolicibacterium smegmatis(MS) expressing Mycobacterium tuberculosis EsxV/W
fusion protein and analyze the phenotype of the recombinant MS and its effect on the macrophage function. Methods: The EsxV/W
fusion protein was obtained by prokaryotic expression, and polyclonal antibody was prepared by immunizing mice with purified EsxV/W
fusion protein. The recombinant strain MS-EsxV/W and the control strain MS-vec were constructed by electroporation, and the
expression of the fusion protein in MS was detected by using the generated polyclonal antibody. The colony morphology, biofilm
formation, and growth rate of the recombinant MS expressing EsxV/W fusion protein were analyzed. The survival ability of the
recombinant MS under different conditions, such as lysozyme, malachite green, low pH, SDS, H2O2 and NaNO2, was determined using
colony counting method to assess the impact of EsxV/W fusion protein on the phenotype of MS. The recombinant MS was used to infect
ANA-1 macrophages. The release of NO from ANA-1 cells was detected by Griess method. Enzyme-linked immunosorbent assay was
performed to measure the release of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) from ANA-1 cells, and the survival
ability of the recombinant MS in ANA-1 cells was determined using colony counting method. Results:The recombinant strain MSEsxV/
W expressing EsxV/W fusion protein, was successfully constructed. The expression of EsxV/W fusion protein had no significant
effect on the colony morphology, biofilm formation and growth rate of MS. The expression of EsxV/W fusion protein did not change the
tolerance of MS to lysozyme, malachite green or low pH, but decreased the tolerance to SDS and increased the tolerance to H2O2 and
NaNO2. After infecting ANA-1 cells for a certain period of time, the release of NO, TNF-α and IL-6 in ANA-1 cells infected by MSEsxV/
W was significantly increased compared with MS-vec, and the intracellular survival ability of MS-EsxV/W was higher than that
of MS-vec. Conclusion:The EsxV/W fusion protein can change the phenotype of MS and regulate the immune response of ANA-1
macrophages, which is conducive to the subsequent investigation of the function of esxV/W gene
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Effects of Saikosaponin D on Uric Acid and Related Enzyme Activity in Rats with Hyperuricemia
Zhang Ping, Fang Qiong
Journal of Dali University 2024, 9 (
2
): 39-42.
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12
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Objective: To investigate the effects of saikosaponin D on the level of uric acid and related enzyme activity in rats with
hyperuricemia. Methods: Saicosaponin D was dissolved in 0.9% sodium chloride solution to prepare 5, 10, and 20 mg/mL solutions.
Fifty SD rats were randomly divided into a control group, a model group, and high, medium and low-dose groups of sausaponin D.
Except for the control group, the remaining rats were administrated with adenine 0.2 g/kg + ethambutol 0.25 g/kg every morning to
establish a hyperuricemia model. The rats in the drug groups were administrated intragastrically at a dose of 10 mL/kg, while the rats in
the control and model groups were administrated intragastrically with the same dosage of 0.9% sodium chloride solution. The levels of
serum uric acid, urinary uric acid, xanthine oxidase (XOD), adenosine deaminase (ADA), creatinine and urea nitrogen were detected
before administration as well as 14, 21 and 28 days after administration. Results: On the 21st day after administration, the serum uric
acid level in the model group rats significantly increased. Compared with the model group, the serum uric acid level of rats in the
medium-dose group of saikosaponin D significantly decreased with statistical significance (P<0.05). On the 28th day after
administration, the serum uric acid level of rats in the high-dose and medium-dose groups significantly decreased, and the urinary uric
acid level of rats in the medium-dose and low-dose groups also decreased significantly. The levels of ADA、XOD、creatinine and urea
nitrogen in all rats of each measurement group of chainu sausaponin D were significantly decreased, and the differences were
statistically significant (P<0.05). Conclusion: Saikosaponin D can inhibit the production of uric acid by reducing the levels of ADA
and XOD, and play a role in lowering uric acid, which has significant renal protective function.
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Teaching Reform of "Molecular Biology" Course Based on the Cultivation of Graduate Students' Scientific Innovation Thinking and Research Quality
Yu Min, Cui Qinghua , Xiong Wei
Journal of Dali University 2024, 9 (
2
): 43-47.
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13
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Innovation ability is the core goal of current graduate education, and cultivating students' scientific innovation thinking in
course teaching is an important part of graduate innovation ability cultivation. In order to meet the country's demand for training
innovative talents in "New Medical Science", the basic course "Molecular Biology" of biomedical majors is taken as an example to
explore a teaching reform mode aiming at cultivating scientific innovative thinking and scientific research quality of graduate students.
Various forms of teaching activities such as case teaching, classic literature analysis, classroom sharing and discussion, academic
reports and special lectures are carried out. The goal is to cultivate students' scientific thinking and innovative thinking, establish a
multiple evaluation system, and comprehensively evaluate the knowledge application ability and scientific research accomplishment of
postgraduates.
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Clinical Study on the Treatment of Subclinical Hypothyroidism in Pregnancy with Levothyroxine Combined with Music Therapy
Zheng Xi, Ma Pinghong, Lu Zhenlan, Wang Zhihui
Journal of Dali University 2024, 9 (
2
): 47-50.
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16
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Objective: To investigate the clinical efficacy of levothyroxine combined with music therapy in the treatment of
subclinical hypothyroidism (SCH) in pregnant women. Methods: A total of 100 pregnant women diagnosed with SCH, admitted to the
department of obstetrics at Xiangcheng People's Hospital in Suzhou from December 2022 to March 2023, were divided into the control
group (treated with levothyroxine alone) and the experimental group (treated with levothyroxine combined with music therapy) using
the random number table method. Thyroid function indicators, lipid metabolism indicators, homocysteine (Hcy) and folic acid levels,
anxiety, depression, and pregnancy complications were compared between the two groups before and after treatment. Results: The serum
thyroid stimulating hormone contents in both groups significantly decreased after treatment(P<0.01), but the intergroup differences were
not statistically significant( P>0.05). There were no statistically significant differences in lipid metabolism indicators, Hcy, and folic acid
levels between the two groups( P>0.05). The anxiety and depression scores in the experimental group improved significantly compared to
the control group, and the incidence of pregnancy complications in the experimental group was significantly lower than that in the control
group (P<0.05). Conclusion: Levothyroxine combined with music therapy can effectively improve anxiety and depression in pregnant
women with SCH, reduce the occurrence of pregnancy complications, and is worthy of further clinical promotion and application.
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Analysis of Minimal Erythema Dose and Photopatch Test in Patients with Chronic Actinic Dermatitis in Dali Region
Yang Chenglin, Hu Jie, Wang Jing, Huang Ling, Wang Minhua,
Journal of Dali University 2024, 9 (
2
): 51-54.
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15
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Objective: To investigate the minimal erythema dose(MED)and photopatch test in patients with chronic actinic dermatitis
(CAD) in Dali region, aiming to explore the differences in the pathogenic spectrum of CAD patients and potential sensitizing
substances. Methods: MED was measured using a solar simulator in 25 CAD patients and 20 healthy volunteers. The photopatch test
was conducted using the RIMIN standard photopatch test reagent kit. Results: The long-wave ultraviolet minimal erythema dose( UVAMED)
for CAD patients was 25.63 J/cm2, and the medium-wave ultraviolet minimal erythema dose(UVB-MED) was 20.56 mJ/cm2. The
UVA-MED for healthy volunteers was 49.92 J/cm2, and the UVB-MED was 38.80 mJ/cm2. The MED values in CAD patients were
significantly lower compared to healthy volunteers(P<0.05). The positive rate of photopatch test in CAD patients was 44%, with
common photoallergens including hexyl 2-(4-diethylamino-2-hydroxybenzoyl)benzoate, promethazine hydrochloride, and 2-hydroxy-
4-methoxybenzophenone. Conclusion: CAD patients are sensitive to both UVA and UVB, and exposure to photocontact allergens may
be an inducing factor for CAD.
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Correlation Analysis of Ultrasound Features in T1-Stage Breast Cancer with the Expression of ER, PR, HER-2, and Ki-67
Wei Wei, Xu Jingya, Feng Huijun, Zhang Xia, Wu Jing, Zhang Wei, Jiang Feng
Journal of Dali University 2024, 9 (
2
): 55-62.
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8
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Objective: To explore the correlation between ultrasound imaging features of T1-stage breast cancer and the expression of
estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER-2), and Ki-67. Methods: A
retrospective collection of medical records of 493 patients confirmed with solitary malignant breast tumors from January 2012 to June
2021 was conducted. Ultrasound features and immunohistochemical results were recorded, and their correlation was analyzed. Results:
The positive rates of ER, PR, HER-2, and Ki-67 were 78.09%, 67.34%, 21.10%, and 71.60%, respectively. ER expression was
positively correlated with PR expression, while HER-2 expression was negatively correlated with ER and PR expression. Ki-67
expression was positively correlated with HER-2 expression and negatively correlated with ER and PR expression. ER-positive
expression was associated with irregular morphology, irregular margins, interstitial fat invasion, and high echo halos in ultrasound
features. PR-positive expression was associated with internal lesion components and axillary lymph node metastasis in ultrasound
features. Ki-67-positive expression was associated with unclear boundaries, interstitial fat invasion, and high echo halos in ultrasound
features, with statistical significance (P<0.05). Conclusion: Ultrasound features of T1-stage breast cancer are correlated with the
expression of ER, PR, and Ki-67. Changes in ultrasound images can provide indications of tumor biological behavior, offering valuable
references for clinical decision-making.
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Application Analysis of Fine Needle Aspiration Biopsy and Intraoperative Rapid Frozen Section in the Diagnosis of Thyroid Nodules
Wang Yan, Hu Huimin
Journal of Dali University 2024, 9 (
2
): 63-66.
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9
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Objective: To explore the diagnostic value of fine needle aspiration biopsy (FNAB) cytology and intraoperative rapid
frozen section histopathology in thyroid nodules. Methods: A retrospective analysis was conducted on clinical pathological data of 180
patients with thyroid nodules treated at Suzhou Xiangcheng People's Hospital from April 2021 to April 2023. The accuracy, sensitivity,
and specificity of FNAB cytology and intraoperative rapid frozen section histopathology were compared and analyzed. Results: FNAB
cytology diagnosed 52 cases of benign lesions and 128 cases of malignant lesions, with an accuracy, sensitivity, and specificity of
92.2%, 91.1%, and 95.6%, respectively. Intraoperative rapid frozen section histopathology diagnosed 55 cases of benign lesions and
125 cases of malignant lesions, with an accuracy, sensitivity, and specificity of 91.1%, 88.9%, and 97.8%, respectively. There was no
statistically significant difference between the two diagnostic methods (P>0.05). Conclusion: FNAB cytology is characterized by
simple operation, high accuracy, and a high specimen acquisition rate. Intraoperative rapid frozen section has the advantages of high
efficiency and clear margin localization. The two methods mutually confirm and complement each other, providing important clinical
value in the diagnosis of the nature of thyroid nodules.
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Correlation Analysis of PRDX2 Expression Changes in Semen and Sperm Motility in Overweight Individuals with Asthenospermia
Xu Guolin, Ye Xiaolin, Qian Tijun, Wang Yuntao, Zhao Wenzhen
Journal of Dali University 2024, 9 (
2
): 67-71.
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6
)
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Objective: To explore the expression of PRDX2 in sperm of asthenospermia individuals with overweight and its correlation
with sperm motility. Methods: A total of 101 semen samples from routine semen analysis at the reproductive medicine department of
the First Affiliated Hospital of Dali University were collected. Samples were grouped into a normal group (60 samples) with normal
body mass and sperm vitality and an overweight asthenospermia group (41 samples) with overweight and asthenospermia. Sperm
routine parameters were measured using a sperm automatic analyzer, and the localization and expression of PRDX2 in sperm from the
two groups were detected by indirect immunofluorescence. Correlation analysis was performed using relevant software to assess the
relationship between PRDX2 expression changes and semen parameters. Results: Indirect immunofluorescence showed that PRDX2
was mainly localized in the midpiece mitochondria of human sperm. The fluorescence expression of PRDX2 in sperm from the
overweight asthenospermia group was significantly lower than that in the normal group. PRDX2 fluorescence expression was negatively
correlated with body mass index (r=-0.857, P=0.002) and positively correlated with progressive motility percentage (r=0.827, P=
0.003). Conclusion: The expression of PRDX2 in sperm is decreased in overweight individuals with asthenospermia, and its
expression is positively correlated with sperm motility.
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Value of Handheld Non-Mydriatic Fundus Photography in Fundus Examination of Patients with Gestational Hypertension
Zha Ruqin, Wang Qiong, Liu Hui, Li Cairui
Journal of Dali University 2024, 9 (
2
): 72-75.
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14
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Objective: To explore the value of handheld non-mydriatic fundus photography in fundus examination of patients with
gestational hypertension. Methods: A total of 111 patients with gestational hypertension were enrolled in the study. They underwent
desktop non-mydriatic fundus photography, handheld non-mydriatic fundus photography, and direct ophthalmoscope fundus
examination. The sensitivity, specificity and accuracy of the other two fundus examination methods in identifying retinal lesions in
patients with gestational hypertension were compared with the results of desktop non-mydriatic fundus examination as the gold
standard, and Kappa tests were performed. Results: The detection rates of retinal lesions by handheld non-mydriatic fundus
photography and direct ophthalmoscope fundus examination were 80.18% and 76.58%, respectively. There was no statistically
significant difference compared with the detection rate of desktop non-mydriatic fundus photography (82.88%). The sensitivity,
specificity, and accuracy of handheld non-mydriatic fundus photography were 94.57%, 89.47%, and 93.69%, respectively, with a
Kappa value of 0.79. The sensitivity, specificity, and accuracy of direct ophthalmoscope fundus examination were 88.04%, 78.95%, and
86.48%, respectively, with a Kappa value of 0.58. Conclusion: Handheld non-mydriatic fundus photography can objectively and
truthfully reflect retinal lesions and can be used as a fundus examination method for patients with gestational hypertension, especially
in bedside fundus examinations that require continuous monitoring.
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Distribution and Drug Resistance of Clinically Isolated Pathogenic Bacteria in Patients with Hematologic Tumors in a Hospital
Zhang Dingcai, Xu Kai, Xu Yu, Yan Jinfang, Li Tianli, Cao Fang
Journal of Dali University 2024, 9 (
2
): 76-80.
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15
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Objective: To analyze the distribution and drug resistance of clinically isolated pathogenic bacteria in patients with
hematologic tumors in a hospital, and to provide medication guidance for empirical treatment of these patients with co-infection.
Methods: Retrospective analysis was used to collect the distribution and drug resistance of pathogenic bacteria isolated from
hospitalized patients with hematologic tumors in the hospital from July 2021 to June 2022, and the results were analyzed. Results: A
total of 86 patients with hematologic tumors were collected, and 124 strains of pathogenic bacteria were detected. Among them, 72
strains were Gram-negative bacteria (58.06%), 49 strains were Gram-positive bacteria(39.52%), and 3 strains were fungi(2.42%).
The most frequently isolated pathogenic bacteria were Escherichia coli with 28 strains(22.58%). The results of drug sensitivity showed
that E. coli had a low resistance rate to carbapenems, while Staphylococcus aureus had a high resistance rate to penicillin and
ampicillin. Conclusion: In the hospitalized patients with hematologic tumors from July 2021 to June 2022, Gram-negative bacteria
were the main isolated pathogenic bacteria, and E. coli accounted for the largest proportion. The drug resistance of pathogenic bacteria
was complex and severe. In order to ensure timely and accurate antimicrobial treatment and improve clinical efficacy, drug-sensitive
detection of pathogenic bacteria in patients should be maintained in clinical practice.
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Analysis of the Current Status and Influencing Factors of Teaching Satisfaction in the Hospital-School Joint Teaching and Research Office of the Affiliated Hospital of Traditional Chinese Medicine
Lin Mu, Jiang Xichao, Meng Wei, Jia Yan, Zhang Handan, Li Xinkun, Yang Zheng
Journal of Dali University 2024, 9 (
2
): 81-84.
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7
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Objective: To investigate the teaching satisfaction of interns, trainees, and newly rotated personnel in the hospital-school
joint teaching and research office, analyze the influencing factors, and propose improvement measures to optimize the teaching
management of the traditional Chinese medicine higher vocational college-affiliated hospital, and enhance the teaching level.
Methods: A total of 721 interns, trainees, and newly rotated personnel in the hospital-school joint teaching and research office of a
traditional Chinese medicine higher vocational college-affiliated hospital in Yunnan were selected as the research subjects. A
questionnaire survey was conducted using Wenjuanxing, and statistical analysis was performed using SPSS 25.0 software. The grade
data were represented by [M (P25, P75)], and the Kruskal-Wallis test was used. Bonferroni correction was applied for post hoc tests.
Results: A total of 701 valid questionnaires were collected. The average age of the research subjects was(20.81±2.30)years. The
satisfaction with the professional level of teaching teachers was the highest, with a score of 4.242, while the satisfaction with rotational
arrangements was the lowest, with a score of 3.838. According to the Kruskal-Wallis test, there were statistically significant differences
in satisfaction with 13 items, including the attitudes of teaching management personnel, teaching management systems, and teaching
facilities among research subjects of different identity categories (P<0.05). According to Bonferroni post hoc test, the satisfaction of
newly rotated personnel was relatively lower than that of interns and trainees. Conclusion: Strengthen the teaching management and
arrangement of the hospital-school joint teaching and research office, formulate different teaching plans and implement classified
management for different types of learners, and scientifically arrange rotational learning.
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Analysis on the Allocation and Equity of Medical and Health Resources in Dali Bai Autonomous Prefecture
Yang Qianwen, Cheng Huizhi, Li Wanying, Zhang Qian, Li Lijuan,
Journal of Dali University 2024, 9 (
2
): 85-89.
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14
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Objective: To understand the current situation of medical and health resource allocation in Dali Bai Autonomous
Prefecture( hereinafter referred to as "Dali Prefecture"), analyze the equity and trend of medical and health resource allocation in Dali
Prefecture from 2015 to 2021, and provide basis for further optimization of medical and health resources. Methods: The Gini coefficient
and agglomeration degree were used to analyze the equity of medical and health resources allocation in Dali Prefecture from the aspects
of number of healthcare institutions, health technicians, practicing (assistant) physicians, registered nurses, and beds. Results: The
level of medical and health resources allocation in Dali Prefecture showed an overall upward trend. The equity of medical and health
resources allocation in Dali Prefecture was poor when the geographical area was used as the evaluation index. When the population
index was used to evaluate the equity, except for the number of healthcare institutions, the overall equity was in a fair state. The
medical and health resources gathered in Dali City were relatively excessive compared with the population, and the other counties were
relatively insufficient. Conclusion: The equity of medical and health resources in Dali Prefecture needs to be improved. Population
and geographical factors should be comprehensively considered to improve the equity of medical and health resources allocation and
rationally plan health investment.
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Application and Evaluation of the O-AMAS Effective Teaching Model in the "Health Assessment" Course
He Qilian, , Ma Xiaolong, Guo Zhifang, Chen Lirong
Journal of Dali University 2024, 9 (
2
): 90-94.
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12
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Objective: To explore the application of the O-AMAS effective teaching model in the "Health Assessment" course and
evaluate the effectiveness. Methods: Nursing students in grades 2020 and 2021 of Dali University were selected as the study objects
and divided into the control group and the experimental group according to teaching mode. The traditional teaching mode was adopted
in the control group, while the O-AMAS effective teaching model was used in the course teaching design for the experimental group.
The results of critical thinking ability, autonomous learning ability, in-class test and teacher-student mutual evaluation were compared
between the two groups. Results: The scores of critical thinking ability, autonomous learning ability, student evaluation, teacher
evaluation and in-class test of the experimental group were significantly higher than those of the control group (P < 0.001).
Conclusion: Integrating the O-AMAS model into the course design of "Health Assessment" can improve the teaching quality and
teacher-student satisfaction, and cultivate students' autonomous learning ability and critical thinking ability. The O-AMAS teaching
model can be applied to other courses as well.
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Analysis of Serum Specific IgE Antibody Results for Allergens in 824 Patients with Atopic Dermatitis
Dai Yu, Shi Hongmei, Ni Changwen, Yang Siqi, Huang Ling, Xu Jing
Journal of Dali University 2024, 9 (
2
): 95-100.
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22
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Objective: To analyze the results of allergen detection in patients with atopic dermatitis (AD) in Dali region, providing
epidemiological data and clinical diagnostic basis for the prevention and treatment of AD in this region. Methods: Clinical data of 824
AD patients were collected, and the results of serum specific immunoglobulin E (IgE) detection for allergens were statistically
analyzed. Results: Among the 824 AD patients, the positive rate of IgE was 35.44%, with 22.94% having one positive item and 12.50%
having two or more positive items. The top five positive rates for inhalant allergens were dust mite mix, mugwort, common ragweed, tree
mix, and cockroach; for food allergens, the top five were egg white, milk, crab, soybean, and peanut. The top three positive allergens
varied among different age groups. In the infants and toddlers group (0-2 years), they were milk, egg white, and beef; in the preschool
children group( 3-6 years), they were dust mite mix, egg white, and mugwort/common ragweed/tree mix; in the school-age adolescents
group (7-18 years), they were dust mite mix, cockroach/mugwort, crab/common ragweed; in the young adults group (19-45 years),
they were dust mite mix, cockroach, and mugwort; in the middle-aged and elderly group (45 years and above), they were mugwort/
common ragweed, dust mite mix, and tree mix. With increasing age, the positive rate of food allergens gradually decreased. Differences
in the positive rates of egg white, milk, peanut, crab, soybean, beef, lamb, dust mite mix, mugwort, cockroach, cat hair, house dust, and
hops among patients in different age groups were statistically significant (P<0.05). The reaction intensity of specific IgE to allergens
was mainly in grades 1-3. Conclusion: The positive rate of serum specific IgE in AD patients is relatively high, mainly mixed type.
Various allergens show significant differences in distribution among different age groups, providing guidance for the prevention and
treatment of AD in the local area.
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Marginal Survival: Research on the Reproduction Field of Miao Costume Culture#br# in the Qimulin Area of Changning, Yunnan#br#
Zuo Yinglong, Li Ruoqing
Journal of Dali University 2024, 9 (
3
): 1-7. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 03. 001
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41
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Taking marginal survivals as the research entry point, and based on the support and guarantee of the national forces
present, this paper focuses on the research object of the Miao costume culture in the Qimulin area of Changning, the national intangible
cultural heritage. It selects the current representative forms of cultural reproduction as samples to discuss the entry of new forces such
as the government and cultural administrators in the living field of Miao costume culture. Without destroying the core strength of
cultural survival in the past as well as the vitality of culture and the field on which the survival of costume culture depends, it tries to
explore how to carry out reproduction actions such as creative transformation and innovative development of Miao costume culture.
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The Spatial Structure of Local Emotions in Ethnic Villages: A Case Study of Shuanglang, Yunnan
Du Fan
Journal of Dali University 2024, 9 (
3
): 8-16. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 03. 002
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27
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With the development of China's economy, the original local landscape of ethnic villages has been disintegrating, which
has also changed the traditional space of villages and the lifestyle of local residents. From the perspective of emotional geography, this
study explores the significance of the emotional structure formed by the Shuanglang residents' local memory and emotion in the
reproduction of local space through field ethnography, and applies Henri Lefebvre's three-dimensional dialectics of history-spiritsociety
to the study of the structure of local emotional space, and draws its emotional space schema and ideal space schema through
tribal drawing. Therefore, the daily living space, emotional space and local emotional characteristics of local residents are
comprehensively studied. The research on the emotional spatial structure of ethnic villages can analyze the local emotional needs of
Shuanglang residents under the promotion of tourism, which is helpful for finding the meaning and value of places for people,
coordinating the relationship between social and economic development and protection of traditional culture, and better reflecting the
nature and characteristics of places.
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On the International Experience of Winning the Supply of Human Resources by Promoting Rural#br# Revitalization Comprehensively:#br# Rethinking Based on the Experience of South Korea's Saemaeul Movement#br#
Liu Chenghao
Journal of Dali University 2024, 9 (
3
): 17-25. DOI:
10. 3969 / j. issn. 2096-2266. 2024. 03. 003
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18
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The report of the 20th National Congress of the CPC has clarified the requirement of comprehensively promoting rural
revitalization. However, considering the current situation of Chinese rural human resources, the comprehensive promotion of rural
revitalization is faced with the dilemma of insufficient supply of effective human resources. As an important component of Chinesestyle
modernization, the promotion of rural revitalization not only includes the strategic arrangement based on the current national
conditions of China, but also has the common experience of the developed countries in the world to realize agricultural and rural
modernization. Therefore, the comprehensive promotion of rural revitalization needs to take care of the international perspective and
Chinese characteristics. China and South Korea are not only geographically close, but also have many similarities in rural issues in the
process of pursuing modernization. Reconsidering the experience of South Korea's Saemaeul Movement to win the participation of
farmers, and ensuring the supply of human resources for comprehensively promoting rural revitalization in China, it is necessary to
innovate the leading role of the government. By improving rural public infrastructure, giving play to the role of network platforms,
promoting the integrated development of rural industries, optimizing agricultural financial policies and the supply of grassroots "threerural"
cadres and talents, and establishing and improving legal norms and other measures, a governance pattern with the coordinated
participation of the whole society can be build.
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