Jiangnan Region and Yunnan Province are two representative areas of ancient town tourism in China. Relying on their rich ancient town resources, prior development consciousness and prominent tourist achievements, Jiangnan Zhouzhuang and Yunnan Heshun have become the ancient town tourism development pronoun in China, and at the same time, the successful "Zhouzhuang Mode" and "Heshun Mode" are followed by many ancient towns for reference. Nevertheless, their tourism development modes are varied due to their distinct differences in regional economy, local culture and spatial organization. Aiming to provide an effective
revelation to the domestic ancient town protection and development, this article compares Zhouzhuang and Heshun from regional economic background, spatial and industry model, and then analyzes the differences of ancient town tourism in different regions.