Table of Content

15 February 2019, Volume 4 Issue 2

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Study on Antimalarial Activity of Embelia ribes and Its Main Constituent Embelin

Cui Shujun, Chen Hao, Liu Jian, Xiao Chaojiang, Shen Lei, Jiang Bei

2019, 4(2):  1-4. 

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〔Abstract〕Objective: To explore the antimalarial activity and the possible mechanism of Embelia ribes and its main constituent
embelin. Methods: The antimalarial activity of the testing samples were evaluated by in vitro and in vivo assays. And β-hematin
formation inhibitory experiment was selected as in vitro assay while 4-day suppression assay of Plasmodium yoelii（BY265RFP）in
mice was used as in vivo assay. Results: Both of the crude extract and ethyl acetate fraction of E. ribes showed good activities with the
suppression rates of 25.25% and 32.17% against P. yoelii in mice, respectively, while the suppression rate of embelin was 41.59% at
the dose of 100 mg/（kg·d）. The results from the β-hematin formation inhibitory experiment indicated that the crude extract of E. ribes
had a certain activity with IC50 = 500.61 μg/mL, but embelin was almost inactive with the IC50 value much bigger than 1 388.89 μg/mL.
Conclusion: Both extract of E. ribes and its main constituent embelin do reveal certain antimalarial activity. The antimalarial activity
of E. ribes should be mainly attributed to embelin, but the antimalarial mechanism of embelin should not come from the pathway of
β-hematin formation inhibition.


Effect of Scutellarin on CYP2C9 in Chang Liver Cells

Ding Weiyao, Chen Liping, Lai Yong

2019, 4(2):  5. 

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〔Abstract〕Objective: To study the effect of scutellarin on the expression of CYP2C9 in Chang Liver cells. Methods: The effect of
scutellarin on proliferative activity of Chang Liver cells was detected by MTT assay. The relative expression of CYP2C9 mRNA and
protein was detected by RT- PCR and Western- blot respectively. Results: MTT results showed that scutellarin inhibited the
proliferation of Chang Liver cells in a concentration-dependent manner, and the half inhibitory rate（IC50）was 1.87 mmol/L. RT-PCR
results showed that the expression of CYP2C9 mRNA significantly decreased in 5.0, 10.0, 20.0, 40.0 μmol/L scutellarin groups（P<
0.05）, compared with DMSO group. Western- blot results showed that the expression of CYP2C9 protein in 20.0, 40.0 μmol/L
scutellarin groups significantly decreased（P<0.05）, compared with DMSO group. Conclusion: Scutellarin has different degree of
inhibitory action on the expression of CYP2C9 mRNA and protein in Chang Liver cells.


Effect of Kangfuxin Liquid on Gut Flora in Rats with Ulcerative Colitis

Zhang Jingna, Li Chaonan, Du Wenwen, Lu Qian, Li Xiuqin, Zhang Chenggui, Li Yue

2019, 4(2):  10. 

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〔Abstract〕Objective: To study the effect of Kangfuxin liquid on gut flora in rats with ulcerative colitis induced by 2，4-
dinitrochlorobenzene combined with acetic acid. Methods: Rat models of UC were established by using DNCB combined with acetic
acid. Groups of UC were treated with Mesalazine, and low, medium and high doses of Kangfuxin respectively. Normal saline was given
to the control group and the model group. After their final treatment rats were sacrificed, and fecal samples were collected.
Fluorescence quantitative PCR was used to detect the changes in the number of major bacterial species in fecal samples of rats in each
group. Results: Compared with the model group, the number of Bacteroides and Bifidobacterium increased in all the groups treated with
Kangfuxin. The number of Lactobacillus increased and the number of Escherichia coli significantly reduced in low-dose Kangfuxin
group; Enterococcus significantly decreased in medium-dose and high-dose Kangfuxin groups（P<0.05）. Conclusion: Kangfuxin
liquid can improve people's gut bacteria and help control ulcerative colitis by increasing the number of probiotics, reducing the number
of opportunistic pathogens and balancing gut flora.

Effect of Kangfuxin Liquid on the Proliferation of Human Skin Fibroblasts

Liu Rongrong, Li Lijuan, Li Yue, Wang Nan, Zhang Haizhu

2019, 4(2):  15. 

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〔Abstract〕Objective: To study the effects of different doses of Kangfuxin Liquid on the proliferation of human skin fibroblasts
（HSF）in vitro. Methods: The human skin fibroblasts were treated with different concentrations of Kangfuxin Liquid and cultured in
vitro, and the cell proliferation was detected by MTT assay. Results: Compared with the negative control group, after 24 h, 48 h and 72
h Kangfuxin Liquid could promote the proliferation of HSF at the concentrations of 3-100 μg/mL. The effect of 48 h and 72 h was timedependent,
and 10 μg/mL culture had the strongest effect after 72 h. Conclusion: Kangfuxin Liquid can stimulate the proliferation of
HSF, and how it promotes the proliferation of HSF needs further study.

Study on the Anti-diabetes Mechanism of Polygonati Rhizoma Based on Network Pharmacology

Xu Feng, Chen Teng, Wang Zuhua, Huang Xulong

2019, 4(2):  21. 

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〔Abstract〕Objective: To explore the anti- diabetic molecular mechanism of Polygonati Rhizoma by network pharmacology.
Methods: The active components of Polygonati Rhizoma were obtained from TCMSP database. The target of Polygonati Rhizoma was
screened by HIT and TTD databases; target dataset was established; OMIM database was used to screen the diabetes-related targets,
and PPI database was used to construct the interactive targets for Polygonati Rhizoma and diabetes. Cytoscape software was used to
construct a "component-target-disease" interactive network map, and the target function and signaling pathway were analyzed by the
GO and KEGG pathways in the DAVID database. Results: The 12 active components of Polygonati Rhizoma were screened, and the
active components of Polygonati Rhizoma were involved in 17 targets including insulin receptor, Caspase-3, inducible nitric oxide
synthase and estrogen receptor, etc. Anti- diabetic effects of Polygonati Rhizoma was regulated by multiple signaling pathways
including PI3K-Akt signaling pathway, AMPK signaling pathway, Insulin resistance, Insulin signaling pathway and Type II diabetes
mellitus. Conclusion: This study demonstrates the multi-component-multi-target-multi-pathway characteristics of Polygonati Rhizoma,
which provides a new idea and scientific basis for further research on the molecular mechanism of anti-diabetic effect of Polygonati
Rhizoma.


UPLC Fingerprints of Periplaneta americana Extract CⅡ-3

Zhou Jiaojiao, Zhang Chenggui, Liu Yuyu, Li Ruoshi, Liu Guangming, Xia Conglong

2019, 4(2):  27. 

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〔Abstract〕Objective: To establish UPLC fingerprints of Periplaneta americana to assess the quality of different batchs of CⅡ-3
samples. Methods: The analysis of Periplaneta americana extract CⅡ-3 was performed in Phenomenex Gemini 5u C18 110A column
（250 mm × 4.6 mm）and the column temperature was 28 ℃. And acetonitrile-water（0.1% formic acid）was the mobile phase of
gradient elution, set at 214 nm wavelength. The quality of C Ⅱ- 3 was assessed according to the similarity evaluation and the
chemometrics method. Results: The UPLC fingerprints of 12 batches of CⅡ-3 were established. There were 21 common peaks and
fingerprints similarity of 11 batches samples was greater than 0.900. Conclusion: It is the first time that the UPLC fingerprint of CⅡ-3
has been established, which provides a scientific basis for the quality control of Periplaneta americana extract CⅡ-3.

Establishment of a Real-time PCR Method for Detection of Gut Bacteria in Patients with Ulcerative Colitis

Duan Xiaomei, Li Chaonan, Geng Funeng, Liu Bin, Zhao Yu, Li Yue

2019, 4(2):  33. 

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〔Abstract〕Objective: To establish a quantitative real-time PCR method for detecting gut bacteria in patients with ulcerative colitis
in order to further explore the effects of imbalanced gut flora on ulcerative colitis（UC）. Methods: We identified 7 gut microbes that
were strongly associated with the pathogenesis of UC. Specific PCR primers were designed to construct a standard recombinant plasmid
containing specific amplified fragments. The absolute quantitative method of real-time PCR was established by using recombinant
plasmids as standards. Results: The real-time PCR method for the detection of such target bacteria as Bifidobacterium, Escherichia
coli, and total intestinal flora, was successfully established. The standard curve of gut bacteria showed a good linear relation with
correlation coefficient ≥0.998. Conclusion: The SYBR Green real-time PCR method can detect seven intestinal bacteria in ulcerative
colitis specifically and provide a convenient and effective method for exploring the correlation between the imbalance of gut bacteria
and UC pathogenesis.


Expression of Human MTERF3 and Its Clinical Value in Cervical Cancer: An Analysis Based on the#br# TCGA Dataset

Mei Wen, Wang Weisi, Sun Meitao, Zhang Tai, Chai Beibei, Zhang Ruopeng, Xiong Wei

2019, 4(2):  38. 

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〔Abstract〕Objective: To explore the expression of human mitochondrial transcription termination factor 3（MTERF3）in cervical
cancer and its clinical value based on the TCGA dataset. Methods：The expression of MTERF3 mRNA and clinical information of
patients with cervical cancer was downloaded from TCGA database. Then the relationship between the expression of MTERF3 mRNA
and clinicopathological characteristics, and the prognostic value of MTERF3 were analyzed by R3.3.0 software; Graphpad Prism 7.01
software was applied to analyze the correlational relationship between the expression level of MTERF3 mRNA and prognosis of patients
by Kaplan-Meier and Log-rank test. Results: The expression level of MTERF3 mRNA was higher in the normal cervical tissues than in
cervical cancers. The expression of MTERF3 mRNA in patients with cervical cancer was not related to age, T stage, N stage and M stage,
but was related to AJCC clinical stage and tumor grade（P < 0.05）. Moreover, there was no difference between the overall survival time
and the disease-free survival of cervical cancer patients and low MTERF3 expression or high MTERF3 expression（Log-rank P＞0.05）.
Univariate analysis showed that T stage, N stage, M stage and clinical stage affected the prognosis of cervical carcinoma（P < 0.05）, but
was not related to age, grade, pathological type and the expression of MTERF3（P > 0.05）. COX multivariate analysis showed that N
stage was an independent factor influencing patients' prognostic. Conclusion: The analysis of the TCGA dataset revealed that the
mRNA expression level of human MTERF3 is related to the clinical stage and tumor grade, but further analysis showed that there is no
significant correlation between the expression level of MTERF3 mRNA and the prognosis of patients with cervical cancer.


Application of Second-line Drugs in the Treatment of Adult Primary Immune Thrombocytopenia

Dong Zhongming, Zhou Chaoyang, Li Peibin, Yang Guobiao

2019, 4(2):  44. 

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〔Abstract〕Objective：To evaluate the safety and efficacy of such second-line drugs as danazol, rituximab and recombinant human
thrombopoietin（rhTPO）in treating adult primary immune thrombocytopenia（ITP）. Methods：The clinical data of 74 patients with
immunological thrombocytopenia were collected. The patients were divided into three groups treated with the three drugs respectively,
and then a retrospective analysis was made. Results: There were no differences between the rhTPO group and the rituximab group（P＞
0.05）, and there were differences between the above-mentioned two groups and the danazol group（P＜0.05）. Conclusion: All the
three drugs are effective. Rituximab group and rhTPO group have the same efficacy and are significantly better than danazol group.


Combination of the Lumbar Sympathetic Nerve Block and Sarpogrelate Hydrochloride in the#br# Treatment of Lower Extremity CRPS-I

Xiong Zhihong

2019, 4(2):  49. 

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〔Abstract〕Objective: To observe the clinical effect of the combination of the lumbar sympathetic nerve block and sarpogrelate
hydrochloride in the treatment of patients with complex regional pain syndrome（CRPS）of lower limbs. Methods: 152 patients with
CRPS type Ⅰ were randomly divided into group Ⅰ and group Ⅱ, 76 cases in each group. Patients in group Ⅰ were treated simply with
lumbar sympathetic nerve block, while patients in group Ⅱ were treated with lumbar sympathetic nerve block combined with
sarpogrelate hydrochloride. The visual analogue scores（VAS）and efficacy of the two groups were evaluated before and after treatment
for 1 and 6 months. Results: There was significant difference in the improvement of symptoms and efficiency between before and after
treatment for 1 and 6 months of treatment（P＜0.05）in the two groups. No complications occurred in both groups. Conclusion:
Lumbar sympathetic nerve block combined with sarpogrelate hydrochloride for CRPS-Ⅰ of lower limbs relieves pain and hyperalgesia,
improves malnutrition symptoms in lower limbs such as weakness, ice-cold, sweating disorder. It is an effective treatment method for
patients with CRPS-Ⅰ.


Diagnosis and Treatment of Poisonous Snake Bites in Honghe Prefecture of Yunnan

Tian Jingmeng, Li Linhui

2019, 4(2):  52. 

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〔Abstract〕Objective: To make a conclusion of the experience of diagnosing and treating bites by venomous snakes in Honghe
Prefecture. Methods: We collected and summarized the data of diagnosing and treating the patients with bites by venomous snakes
admitted in the First People's Hospital of Honghe Prefecture during the recent six years. Results: The combination of adder antivenom
and coral snake antivenom was an effective treatment for bites by most of venomous snakes in Honghe Prefecture. Conclusion: Adder
antivenom combined with coral snake antivenom can be taken as the method of treating bites by venomous snakes within the region.


Clinical Analysis of the Feasibility of Vaginal Delivery for 68 Patients' Subsequent Pregnancy in#br# Scarred Uterus

Yang Sili, Wang Bin, Wang Jianping, Luo Wanxun

2019, 4(2):  55. 

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〔Abstract〕Objective: To study the feasibility of vaginal delivery for subsequent pregnancy in scarred uterus. Methods: We explored
the outcomes of planned VBAC and non-scar vaginal delivery, ERCS and first cesarean section delivery in Dali Teaching Hospital of
Dali University from January 2017 to December 2017. Results: Out of 434 patients with scarred uterus, 68 had TOLAC, 54 had VBAC,
and the success rate was 79.4%. No significant difference was found between TOLAC and non-scar vaginal delivery（P > 0.05）. There
was a significant difference between ERCS and the first cesarean section（P < 0.05）. Conclusion: Compared with ERCS, VBAC can
reduce postpartum bleeding, shorten hospitalization time, have good maternal and child outcomes, and reduce cesarean section rate. It
is necessary to strengthen the management of the subsequent pregnancy after cesarean section, make emergency plans, strictly control
the indications, eliminate contraindications, have proper communications, and offer correct childbirth guidance in order to effectively
reduce the rate of cesarean section and the incidence of maternal and infant complications.


Clinical Application of Conbercept for Treatment of Diabetic Retinopathy and Macular Edema

Cheng Fei, Jia Yunqin, Han Peiyan, Chen Yinchao, Zhou Xia, Duan Zhiguang

2019, 4(2):  59. 

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〔Abstract〕Objective: To evaluate the efficacy and safety of Conbercept intravitreal injections in treatment of diabetic retinopathy,
and its effects on vitrectomy for proliferative diabetic retinopathy（PDR）. Methods: We retrospectively analyzed 56 patients（80 eyes）
with DR who received Conbercept intravitreal injection in our hospital. 30 patients（62 eyes）had NPDR, and 26（28 eyes）with severe
PDR underwent vitreous resection（PPV）. The latter was randomly divided into the IVC&PPV group in which 15 patients（16 eyes）
were treated with conbercept intravitreal injection in combination with vitrectomy and the PPV group in which 11patients（12 eyes）
underwent vitrectomy. Results: Among patients with NPDR, their diabetic retinopathy was improved in varying degrees,
neovascularization was significantly inhibited, macular edema was improved and absorbed, and visual acuity was corrected in different
degrees. IVC/PPV was significantly favorable for surgical operations. Conclusion: Intravitreal injection of Conbercept is an effective
treatment for NPDR. For severe PDR patients who are undergoing vitrectomy, it can effectively reduce the difficulty of surgery and
reduce the occurrence of surgical complications, so it is the mainstream choice for the treatment of diabetic retinopathy.


Investigation of Mycoplasma Pneumoniae Infection in Patients with Pneumonia in Dali

Duan Pengyuan, Li Liuqin, Song Zhizhong, Wang Peng

2019, 4(2):  65. 

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〔Abstract〕Objective: To screen the cases with Mycoplasma pneumoniae pneumonia （MPP）in patients with community-acquired
pneumonia （CAP） by using quantitative real time polymerase chain reaction （qPCR）, and to describe clinical, demographic,
laboratory and imaging characteristics of MPP. Methods: A total of 182 patients with CAP who were admitted to Dali Teaching
Hospital of Dali University（the First People's Hospital of Dali）from August 2017 to February 2018 were selected. The respiratory
specimens of above subjects were detected by qPCR according to primers for RepMP1 gene, and the clinical data of those 182 patients
were collected. Results: Positive MPP was detected in 12 cases. By analyzing the clinical data of these patients, we found that the
common symptom of these patients was fever, and their C reactive proteins were higher than non-MPP patients. Conclusion: The
qPCR can be applied to the detection of MPP. In addition, the C reactive proteins of MPP patients are higher than non-MPP patients,
which can provide some references for clinical diagnosis and treatment.


Analysis of the Attainment Rate of Serum Calcium, Phosphorus and Intact Parathyroid Hormone Levels#br# in Peritoneal Dialysis Patients

Zhao Xian, Liu Liru, Cui Min, Zhao Meizhu, Zhang Yu, He Minhua

2019, 4(2):  70. 

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〔Abstract〕Objective: To investigate the attainment rate of calcium, phosphorus and intact parathyroid hormone（iPTH）levels in
peritoneal dialysis（PD）patients from the First Affiliated Hospital of Dali University, and to explore the effect of residual urine volume
on calcium & phosphorus metabolism. Methods: We collected the clinical data of 88 patients from October 2017 to March 2018 who
received PD for more than 3 months and had regular follow-up in our blood purification center and made a cross-sectional study. The
attainment rates of serum calcium, phosphorus and iPTH levels were calculated according to K/DOQI standard, and compared with the
results from the domestic and foreign studies. According to the residual urine volume patients were divided into two groups（urine
volume <100 mL/d for the anuria group, urine volume ≥100 mL/d for the urine group）, and then serum calcium, phosphorus and iPTH
levels between the two groups were compared. Results: The proportions of patients who have reached the normal serum calcium,
phosphorus and iPTH concentrations were 44.3%, 40.9% and 12.5%, respectively. 4.5% patients reached all the target levels for
calcium, phosphorus and iPTH. The attainment rates of calcium and phosphorus in our research was similar to the results of other
studies, but the attainment rate of iPTH was comparatively lower. Serum phosphorus and the calcium - phosphate product
concentrations of the patients without urine were higher than those of the urine group（P<0.05）. Conclusion: The control of calcium
and phosphorus metabolic disorder and secondary hyperparathyroidism in PD patients in our center is poor, which needs to be further
strengthened.


Diagnostic Value of High-frequency Superficial Color Doppler Ultrasound in Nodular Goiter

Yan Na, Liu Biaohu, Xu Yingying, Zhu Xiangming

2019, 4(2):  76. 

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〔Abstract〕Objective: To explore the clinical value of high-frequency two-dimensional superficial ultrasound and color Doppler flow
imaging（CDFI）in diagnosing nodular goiter. Methods: 96 patients with suspected nodular goiter were examined by high-frequency
two-dimensional ultrasonography and color Doppler flow imaging. The follow-up pathological results and the typical ultrasonography
map features were analyzed retrospectively. Results: Among 96 cases of patients with nodular goiter diagnosed by ultrasound, the
diagnosis of nodular goiter of 72 was confirmed by surgery and pathology, 5 cases were diagnosed as thyroid adenoma and 5 cases were
confirmed as thyroid papillae cancer by pathology. The diagnostic accuracy rate of ultrasonography was 75%. Conclusion: Highfrequency
two-dimensional superficial ultrasound combined with color Doppler flow imaging has a high diagnostic rate of nodular
goiter. This diagnostic method is non-invasive, non-radiative, safe and reliable, and can be used as the preferred imaging method for
examining nodular goiter.


A Correlative Analysis of Ultrasound-detected Calcification in#br# Thyroid Nodules and Thyroid Cancer

He Cuiyun, Zhou Hongwei, Wu Xiaoxiao, Zhang Yanhua, Li Yaping

2019, 4(2):  79. 

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〔Abstract〕Objective: To explore the correlation between ultrasound-detected calcification in thyroid nodules and thyroid cancer.
Methods: We conducted a retrospective review of ultrasonic images of thyroid nodules of 229 patients with thyroid cancer hospitalized
in the People's Hospital of Yuxi from Jan. 2010 to Oct. 2017, and applied the same criteria to evaluate whether there were ultrasound
calcifications in thyroid nodules and analyzed the features of calcification. Results: Ultrasound calcifications were detected in 147
（64.19%）of all cancerous nodules, while in 82 of the 229（35.81%）nodules no ultrasound calcifications were found. The differences
between the two groups of data were statistically significant（P＜0.05）. Among the patients with ultrasound calcifications the incidence
of micro- calcifications was 95.92%（141/147）, which was clearly higher than the incidence of coarse calcifications and ring
calcifications of 4.08%（6/147）. There was statistically significant difference（P＜0.05）. Conclusion: There is a great clinical value
in diagnosing thyroid cancer by detecting ultrasound micro-calcifications in thyroid nodules. But the risk of malignant nodules in
coarse calcifications and ring calcifications is still high. Thus, in order to promote accurate diagnosis, FNA should be performed on the
ultrasonographically suspicious nodules if necessary.


Quality of Life Survey of Elderly Migrants of Yi Nationality in Yunnan Province

Zhao Guifeng, Zhao Yuan, Yang Liangying, Zhao Yanjuan

2019, 4(2):  82. 

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〔Abstract〕Objective: To survey the quality of life of senior migrants and senior natives from Yi ethnic group in Yunnan, and explore
the essential factors affecting their quality of life. Methods: We randomly selected 60 senior migrants and another 60 senior natives
from Yi ethnic group in Yunnan as the subjects. Surveys were conducted by using social demographic data questionnaires and the
generic scale WHOQOL-BREF developed and recommended by WHO. Results: There were no statistically significant differences in
self-rating score of quality of life and health status between senior migrants and senior natives of Yi Nationality(P>0.05); but such
factors as age, average monthly family income and chronic diseases influenced the quality of life of senior migrants (P<0.05).
Conclusion: There are no differences between the quality of life of senior migrants and senior natives of Yi Nationality in Yunnan.
Age, average monthly family income and chronic diseases are the major factors that have influenced life of quality of senior migrants of
Yi nationality.


Meta-analysis on the Effects of Alcohol Consumption on Arsenic Metabolism and Methylation

Sun Mingjun,Wu Xiumei, Qu Tengjiao, Gao Zhangjin, Zhao Qingyun, Wen Weihua

2019, 4(2):  86. 

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〔Abstract〕Objective: To evaluate the effects of alcohol consumption on arsenic metabolism and methylation capacity of the
population exposed to arsenic by Meta-analysis. Methods: Used the computer to search the articles about the effects of alcohol on
arsenic metabolism and methylation in CNKI, PubMed, Medline, VP and Wanfang databases. Review Manager 5.3.5 software was used
for Meta-analysis. Results: A total of 9 articles were analyzed, including 4 077 subjects. The result of Meta-analysis showed that the
iAs%, MMA% ,DMA% ,PMI and SMI in urine of the drinking group were 0.72,1.42,-2.27, 0.07,-1.54 and 95%CI were［0.14,1.31］,
［0.84,2.00］［, -3.32,-1.22］［, -0.16,0.29］［, -1.91,-1.17］, respectively. It was shown that iAs% and MMA% of the drinking group were
higher than the non-drinking group, but DMA% and SMI were lower. Conclusion: Alcohol consumption may be one of the factors
influencing arsenic metabolism and methylation of the population exposed to arsenic.


The Influence of Humanized Design in Gynecology and Obstetrics Department on Humanistic Nursing#br# Level of Nursing Students

Chen Liyu

2019, 4(2):  93. 

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〔Abstract〕Objective: To improve the humanistic nursing care level of nursing students, and lay a sound foundation for a highquality
nursing service. Methods: 60 senior nursing students were selected from the nursing College, Dali University; CAI was used to
evaluate their basic information and humanistic caring ability. According to the evaluation results, they were divided into the
observation group and the control group on average. The control group was assigned to a maternity hospital with a traditional pattern
and the observation group was assigned to a gynecology and obstetrics hospital with a humanized pattern. Nursing students of the two
groups conducted routine nursing procedures in both hospitals for three months. After that, CBC was used to evaluate the humanistic
care level of the students in the two groups again. Results: The total CBC score of the observation group was 239 and the total CBC
score of the control group was 182. Conclusion: The design of humanized care unit in obstetrics and gynecology department can
improve the humanistic nursing care level of nursing students.


Clinical Application of Graphic Type Health Education Path in Patients Undergoing Scoliosis Orthopedics

Chen Li, Na Qiang

2019, 4(2):  97. 

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〔Abstract〕Objective: To discuss the effect of graphic type health education path applied in patients who underwent scoliosis
orthopedics. Methods: 40 patients who underwent scoliosis orthopedics between January 2012 and December 2017 in the first
department of orthopedics in the People's Hospital of Yuxi City were randomly divided into the observation group and the control group
on average. In the control group the traditional lecture method of teaching health education was adopted, while in the observation group
the method of graphic type health education path was performed to offer systematic, planned and targeted health education. Before
discharge patients in both groups were distributed with self-made questionnaires and surveyed about their mastery of health knowledge
and satisfaction with nursing care. Results: Compared with the control group, patients in the observation group had a better
understanding of health knowledge and rehabilitation exercise, and had a higher satisfaction with nursing care. The difference between
the two groups was statistically significant（P < 0.05）. Conclusion: The teaching method of graphic health education path has better
effect than the traditional lecture method, improving the quality of health education and nursing care, and enhancing the patients'
satisfaction degree.