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Table of Content

    15 February 2017, Volume 2 Issue 2
    Research of Extracts from Periplaneta americana on Reversing Multi-drug Resistance to Bel-7402/5-Fu
    Li Ting, Qiao Tingting, Liu Junyong, Shen Qi, Peng Fang
    2017, 2(2):  1-5. 
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    Objective: To investigate the effect and mechanism of extracts from Periplaneta americana on reversing multi- drug
    resistance to Bel-7402/5-Fu. Methods: Multi-drug resistance to cancer agents and nontoxic dose of the Periplaneta americana extract
    CⅡ-3 and skim cream were evaluated by MTT assay. The effect of mitochondrial membrane potential and expressions of Bcl-2, Bax,
    Caspase-9 and Caspase-3 were detected in Bel-7402/5-Fu cells affected with CⅡ-3 and skim cream. Results: Bel-7402/5-Fu cells
    showed high resistance to 5-Fu, the resistance ratio was 66.42. The dose of CⅡ-3 was lower than 93.37 μg/mL, and the dose of skim
    cream was lower than 47.81 μg/mL. CⅡ-3 and the skimmed cream could decrease mitochondrial membrane potential and CⅡ-3 was
    stronger than the skimmed cream. CⅡ-3 and the skimmed cream could inhibit the Bcl-2 protein expression of Bel-7402/5-Fu and the
    inhibition effect increased with the dose amount; could promote the expression of Bax protein and the promoting effect increased with
    the dose amount; could activate downstream pathways of Caspase-9, Caspase-3, and the promoting effect increased with the dose
    amount. Conclusion: The Periplaneta americana extract CⅡ-3 and the skimmed cream can effectively reverse MDR in Bel-7402/5-
    Fu cells. The mechanism is to decrease of mitochondrial membrane potential, and regulate the expression of Bcl-2, Bax, Caspase-9
    and Caspase-3 protein.

    Effects of Vicatia thibertica de Boiss on Immunologic and Hematopoietic Function of Mice
    Lyu Hong, Guo Meixian Yang Qiaoling, Yang Jiao, Shen Lei, Du Yimin, Liu Xiaobo
    2017, 2(2):  6-10. 
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    Objective: To study the effect of ethanol extracts of Vicatia thibertica de Boiss on immunologic and hematopoietic
    functions of cyclophosphamide-induced immunosuppressed mice. Methods: Immunosuppressed mice were induced by intraperitoneal
    injection of cyclophosphamide and were treated intragastrically with different doses of Vicatia thibertica de Boiss. After treatment, the
    immune organ weight and index of mice, the carbon clearance ability of mice, the levels of hepatic SOD and MDA, the routine blood
    examination, and the contents of serum hemolysin were tested. Results: Compared with the model group, high, medium and low dose of
    ethanol extracts of Vicatia thibertica de Boiss improved the immune organ weight and index, and the carbon clearance ability of mice,
    enhanced the levels of hepatic SOD and MDA, increased the content of leukocytes and platelet in peripheral blood content and raised
    the content of serum hemolysin. Conclusion: The ethanol extracts of Vicatia thibertica de Boiss could enhance the immunologic and
    hematopoietic functions of cyclophosphamide-induced immunosuppressed mice.

    Research on Anti-tumor Activity of Iron-fluorouracil Complex
    Du Xin'e, Zhou Yun, Chen Yingjie, Shi Min, Zhong Wenyuan, Zhou Yiping
    2017, 2(2):  11-19. 
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    Objective: To explore iron- fluorouracil complex's anti- tumor activity and effect to human gastric carcinoma cells
    apoptosis. Methods: MTT method was used to detect inhibition rate of the complex on tumor cell lines: K562, HCT-116, SGC-7901,
    MCF-7 and HEPG-2; Hoechst 33342/PI and flow cytometry(FCM)methods were used to exhibit apoptosis of SGC-7901 cells; RTqPCR
    was used to measure the mRNA expression of apoptosis related factors: Caspase-3, Bax and Bcl-2. Results: Iron-fluorouracil
    complex obviously inhibited the proliferation of 5 tumor cell lines. IC50 were 7.8×10-5, 5.4×10-5, 3.5×10-5, 1.1×10-4 and 2.2×10-5 mol/L,
    respectively. After 36 hours' treatment on SGC-7901 cell with a concentration 10- 5 mol/L, its apoptosis rate was 9.8%, which could
    promote SGC-7901 cell apoptosis than its ligands 5-Fu and Phen(P<0.01); the mRNA expression of Caspase-3 gene was up-regulated
    to 4.9(P<0.01), while Bcl-2 was down-regulated to 0.2(P<0.01). Conclusion: The complex showed good anti-tumor activity in
    vitro, up regulation of Caspase-3 as well as down regulation Bcl-2 may be one of its mechanisms of action.

    Study on the Quality Standard of Qingfei Yihuo Tablet
    Shao Weizai, Duan Zhishang, Wan Desheng, Que Yuling, Zhou Yongbin
    2017, 2(2):  20-23. 
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    Objective: To develop a method for revising and improving the quality standards of the Qingfei Yihuo Tablet. Methods:
    Microscopic identification and TLC method were adopted to identify the quality of the Dahuang, Jugeng, Huangbo and Kusheng in
    preparation and analyzing the Huangqigan in Huangqi by the method of HPLC. The analysis was performed on an Agilent TC-C18
    column with the mobile phase consisting of methanol(A)−0.4% phosphate acid(53:47)by gradient elution at a flow rate of 0.6
    mL/min. The detection wavelength was set at 280 nm and the column temperature was 30 ℃. Results: Calcium oxalate crystal clusters
    were checked out by the method of microscopic identification, the diameter of Dahuang was 60-140 microns and the shape of Jugeng
    was inulin fan or quasi-circular. Additional, Dahuang, Huangbo and Kusheng were detected out by the methods of TLC and the HPLC
    results showed that the linear ranges were 0.025-4.000 μg/mL(r=0.999 8)for Huangqigan. The average recoveries(n=9)were
    99.8%, RSD=0.34%. Conclusion: The developed method is accurate, reproducible and specific and the quality of the preparation can
    be controlled.

    Infrared Spectrum Analysis on Trichosanthes kirilowii Maxim and Its Processed Products
    Zong Qianni, Wang Jing, Xu Qixiang, Zou Chuncai, Yan Haiyan
    2017, 2(2):  24-30. 
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    Objective: To analyze the influence of processing methods on chemical constituents in Trichosanthes kirilowii Maxim.
    Methods: The chemical differences of Trichosanthes kirilowii Maxim before and after processing were analyzed by Fourier Transform
    Infrared Spectrum(FTIR)and the main chemical composition was identified. Results: Infrared spectra of Trichosanthes kirilowii
    Maxim and its processed products were similar. The IR characteristic absorption peaks of certain constituent are found: 1 240 cm- 1
    (δOH), 3 300-3 420 cm- 1(νOH of flavonoids and polysaccharide, glycosides, or alcohol O-H), 2 853-2 930 cm- 1(νCH of methyl or
    methylene C-O)and 1 510-1 660 cm-1(δNH of protein N-H or νC-C of aromatic compounds benzene ring)and 1 050 cm-1(flavonoids
    or νC- O of polysaccharide and glycosides). The second derivative spectra of Trichosanthes kirilowii Maxim and its processed products
    revealed more fingerprint peaks, which helps to separate Trichosanthes kirilowii Maxim and its processed products. Conclusion: The
    chemical composition of Trichosanthes kirilowii Maxim had little changes after the processing procedure, and the second derivative
    spectra offered better identification of Trichosanthes kirilowii Maxim and its processed products.

    Meta-analysis of the Efficacy and Safety of Voriconazole as Anti-fungal Prophylaxis in Invasive Fungal
    Infection after Hematopoietic Stem Cell Transplantation(HSCT)
    Mao Panpan, Du Yimin, Zhang Yang, Lu Wei, Li Xingde, Song Cangsang
    2017, 2(2):  31-36. 
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    Objective: To systematically review the efficacy and safety of voriconazole what was used to prevent the invasive fungal
    infection by patients after hematopoietic stem- cell transplantation. Methods: The PubMed, Medline, Cochrane Library, EMbase,
    CNKI, CBM, Wangfang, VIP databases were searched to find out the randomized controlled trials about the efficacy and safety of
    voriconazole as anti-fungal prophylaxis of invasive fungal infection after hematopoietic stem-cell transplantation. Quality and extracted
    information of the clinical trials were evaluated. Meta-analysis was performed using RevMan 5.3 software. Results: 4 RCTs were
    included, involving 1 325 patients. Results of Meta-analysis showed: voriconazole could reduce IFI after hematopoietic stem-cell
    transplantation[RR=0.57, 95% CI(0.38, 0.86), P<0.01]and decrease the incidence of ADR[RR=0.78, 95% CI(0.64, 0.95), P=
    0.01]. There was no statistical significance in mortality among voriconazole, fluconzole and itraconzole[RR=0.84, 95% CI(0.58,
    1.20), P=0.33]. Conclusion: Voriconazole as anti- fungal prophylaxis of invasive fungal infection can effectively reduce the
    occurrence of IFI and ADR after hematopoietic stem-cell transplantation.

    Pharmacognostical Study of Silene delavayi Franch
    Li Mao, Zhang Zhongyuan, Wang Weiwei, Jiang Wei, Zhang Yang, Yang Yue'e
    2017, 2(2):  37-39. 
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    Objective: To conduct a pharmacognostical study of Silene delavayi Franch. Methods: Original plant, character
    identification, microscopic identification and physicochemical identification methods were used. Results: The original plant
    morphology, character feature, cross section structural and powder microscopic characteristics, and preliminary analysis of physical and
    chemical components of Radix Silene delavayi were described. Conclusion: The results provide basis for the identification and quality
    evaluation of this crude drug.

    Bioinformatics Analysis of hMTERF3 Gene Promoter Region
    Sun Meitao, Wang Yun, Li Yue, Zhang Xiaojuan, Yang Yongqin, Yang Zefang, Xiong W
    2017, 2(2):  40-45. 
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    Objective: To investigate the characters, transcription factors and their binding sites of human mitochondrial transcription
    termination factor 3(hMTERF3)gene promoter by different bioinformatics tools. Methods: Promoter 2.0, NNPP, Proscan, and FirstEF
    softwares were used to analyze the numbers and distributions of hMTERF3 gene promoter; CpG Islander and CpG Plot softwares were
    used to analyze the GpG island of hMTERF3 gene promoter; P-match 1.0 protocol and TRANSFAC database were used to analyze the
    transcription factors and their binding sites of hMTERF3 gene promoter. Results: hMTERF3 gene was located on 8q21.2. The full
    length of hMTERF3 gene was 22 216 bp, consisting of 11 exons and 10 introns. There were at least two promoters in the 5' unconding
    region of hMTERF3 gene. The core promoter of hMTERF3 gene was located between 1 733-2 302 bp, containing TATA box. In
    hMTERF3 gene promoter region, a 1 145 bp CpG island could be found. In addition, 1 055 transcription factor binding sites were
    predicted by P-Match 1.0 protocol, and only 19 transcription factor binding sites were found in conserved core promoter region of
    human and mouse homologous MTERF3 genes by phylogenetic foot- printing analysis. Conclusion: Gene promoter related
    bioinformatics analysis can improve the efficiency of hMTERF3 gene promoter research, and provide significant information for the
    construction of promoter expression vector, also for the further study of promoter function.

    Research on Progress of the Influence of Cell Signaling Pathway on Hepatic Fibrosis
    Yang Kaiming, Jiang Wenjuan, Cheng Jiamao
    2017, 2(2):  46-50. 
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    Objective: To investigate the role and mechanism of cell signaling pathway in the occurrence and development of hepatic
    fibrosis. Methods: The literature about the regulation of cell signaling pathway and its mechanism in recent years were reviewed.
    Results: Hepatic fibrosis is a pathological repair reaction to the chronic liver damage. Cell signaling pathways like TGF-β, PDGF,
    hedgehog signaling, Wnt signaling, JAK-STAT and Notch signal participated in the occurrence and development of hepatic fibrosis.
    Conclusion: Hepatic fibrosis is the result of a series of cell signaling pathways: hedgehog signal, Wnt signal and a series of cell
    information molecules.

    Clinical Analysis of 128 Tibetan Patients' Coronary Arteriongraphy Data from Western Yunnan
    Chen Yu, Song Fugang, Wen Xingyang, Mu Sen, Yang Guangcheng
    2017, 2(2):  51-54. 
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    Objective: To investigate the mechanism and prevention methods of Tibetan coronary artery patients by comparing the
    clinical data of Tibetan and Han patients. Methods: From July 2007 to June 2014, 128 Tibetan and 118 Han patients received
    coronary arteriongraphy in our hospital, and their imageology and clinical data was retrospectively analyzed. Results: The rate of
    Tibetan patients(52.35%)with multiple branches(≥2)is significantly higher than that of Han patients(37.29%)(P<0.05).
    62.71% of Han patients are with single branch affection. The amount of Tibetan patients with coronary artery ectasia(52.35%)is
    significantly more than that of Han(33.05%)(P<0.05). The proportion of Tibetan patients with corpulence and hyperlipemia is
    higher than Han(P<0.05). The platelet count of Tibetan patients[(262.37±70.56)109/L]is significantly higher than that of Han
    [(233.80±64.55)109/L](P<0.05). Conclusion: The incidence of coronary artery ectasia of Tibetan is higher than Han, the risk factor
    like overweight and hyperlipemia should be controlled.

    Literature Review of 15 Cases of Duodenal Heterotopic Gastric Mucosa
    Guo Shunhong, Tao Zhongyuan, Du Guiying, Zhang Qinyuan, Zheng Qingmei
    2017, 2(2):  55-57. 
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    Objective: To investigate the clinical feature and diagnosis with endoscope of duodenal heterotopic gastric mucosa.
    Methods: Retrospective analysis was conducted among the clinical and endoscope data of 15 cases duodenal heterotopic gastric
    mucosa in the Endoscopy Center of The First People's Hospital of Dali City from February 2012 to August 2015. Results: Duodenal
    heterotopic gastric mucosa is in the duodenal under the helicobacter, which shows particles hyperplasia or polypoid as well as single
    polypoid. Pathology shows heterotopic gastric mucosa. Conclusion: Polypoid hyperplasia was very common under endoscope.
    Coincidance rate of

    Clinical Research on Surgical Treatment and Prognostic of Acute Limbs Ischemia
    Xie Siyuan, He Xiaoming, Wang Shaobo, Liu Rengui
    2017, 2(2):  58-60. 
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    Objective: To investigate the cause and method of effective clinical treatment and prognosis of acute limbs ischemia.
    Methods: Fogarty catheter thrombectomy and anticoagulation therapy were used on 31 cases of acute limbs ischemia within 6 years in
    a certain hospital. Results: Among 31 cases, 26 cases' ischemia symptom disappeared or were improved, 5 cases had irreversible
    necrosis because of long term of critical ischemia pre-operation, received second phase amputation post-operation. Conclusion: The
    embolectomy surgical treatment and anticoagulation therapy are effective clinical methods of the patients who have acute limbs
    ischemia after the evaluation of the reason, degree and scope of ischemia. It's necessary of being careful in assessing the amputation
    level to avoid amputation again.

    Efficacy Analysis of Caffeine Citrate on Primary Apnea in Premature Infants
    Yang Jie, Yang Xiuling, Qi Huixian, Shu Lei
    2017, 2(2):  61-63. 
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    Objective: To investigate efficacy and safety of caffeine citrate for treating primary apnea in premature infants. Methods:
    A retrospective analysis was conducted among clinical data of 92 cases of apnea in premature infants of 27-32 weeks in NICU during
    November 2014 to October 2015. They were divided into two groups: observation group of caffeine citrate treatment(n=52)and the
    control group of aminophylline treatment(n=40). A comparison of the effectiveness of two apnea treatment and adverse reactions
    incidence rate of tachycardia, hyperglycemia, irritability, bloating and gastric retention were done. Results: The clinical total effective
    rate of the observation group was 90.4%, which was 70.0% higher than the control group. The difference was statistically significant
    (P<0.05). The rate of tachycardia, hyperglycemia, irritability, bloating, gastric retention during treatment of the observation group was
    lower than the control group(P<0.05). Conclusion: Caffeine citrate has significant effect on treating premature infants of primary
    apnea, reducing the incidence of apnea, causing fewer adverse events and improving prognosis.

    Comparative Analysis of Fibroscan in Diagnosis of Liver Fibrosis with Chronic Hepatitis B and
    Pathologic Stage
    Chen Duanzhen, Pang Xingmei, Dong Zhijian, Song Wenjuan, He Weiyaozhen
    2017, 2(2):  64-66. 
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    Objective: To investigate the accuracy of transient elastography(Fibroscan)detection to liver fibrosis with chronic
    hepatitis b(CHB). Methods: 71 cases of hospitalization patients with chronic hepatitis b were collected from February to October
    2015. Fibroscan was applied to detect liver stiffness measurement(LSM), and ultrasonic positioning was used at the same time, then
    the liver stiffness measurement(LSM)and hepatic fibrotic staging were compared. Results: LSM(kPa)of S0-1, S1, S1-2/S2, S2-3/S3,
    S3-4/S4 were(4.16±1.53),(4.60±1.06),(5.84±2.82),(12.09±6.41)and(13.03±3.43), respectively, which was positively related to
    the liver fibrosis stage(S). Tested by the rank and Kruskal Wallis test, the result is χ2=28.233 7, P<0.05. Conclusion: Fibroscan has
    high diagnostic value for liver fibrosis of CHB.

    Clinical Application in Diagnosis of Fetal Congenital Heart Disease by Fetal Venous Catheter Spectrum
    with Ultrasonic Detection
    Wu Wenxia, Li Peixuan, Xiong Deqing, Shen Junling, Li Hong
    2017, 2(2):  67-69. 
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    Objective: To evaluate the clinical application of fetal venous catheter in diagnosis of fetal congenital heart disease with
    different gestational age. Methods: 4 060 cases of fetal venous catheter flow parameters were detected in 11 to 40 gestational weeks,
    including PVD(ventricular systole peak velocity), PVS(ventricular diastolic peak flow velocity), PVA(atrial systolic maximum
    velocity), PI(pulsatility index), RI(the resistance index), PVIV(venous peak velocity index)and S/A. Results: 26 cases of
    abnormal venous frequency spectrum were detected by ultrasonic examination, all of them were diagnosed with the fetal congenital
    heart disease. A waves of venous catheter were inversed in 16 cases and were missed in 10 case. The diagnosis was completely in
    accordance with the autopsy or the neonatal cardiac ultrasonic contrast. Conclusion: The ultrasonic detection of fetal venous catheter
    spectrum was an effective method for diagnosis of fetal congenital heart disease.

    Survey and Analysis of Food Safety Status of Rural Residents in a Yi Autonomous County in
    South Sichuan
    Deng Bo, Wu Hanqi
    2017, 2(2):  70-73. 
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    Objective: To investigate the status of knowledge, attitude and practice(KAP) about food safety among the rural
    residents in a Yi autonomous county in south Sichuan, and to provide a theoretical basis for further health education and behavior
    intervention among the rural residents. Methods: The respondents were randomly selected from four villages in Ebian County.
    Questionnaires were used to collect data on food safety knowledge, attitude and practice. Results: Most local Han and Yi people were
    lack of food safety knowledge. The awareness rate of food safety knowledge was 25.5%-97.8%. A small number of the local people fully
    believed in the integrity of the food business operators(Han nationality 12.4%, Yi nationality 19.3%). About half of the people would
    choose to complain about the poor-quality the food(Han nationality 51.3%, Yi nationality 56.9%). About 53.1% of respondents use
    separate tools in kitchen for raw food and cooked food(Han nationality 53.2%, Yi nationality 52.3%). Conclusion: The rural residents
    of Ebian had many problems on food safety. So it is quite necessary for them to be instructed the knowledge of food safety to improve
    the current food safety situation in local.

    Study on the Relationship between Life Style and Quality of Life of the Primary School Teachers
    Li Jiangyan, Li Ling, Zhang Xiaoyun, Li Canwei, Chen Hongyun
    2017, 2(2):  74-79. 
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    Objective: To study on the correlation of life style and quality of life of 9 dimensions among primary school teachers in the
    mountain area of Tengchong and Longling county in Yunnan for improving primary school teachers' life style and quality of life.
    Methods: SF-36 Quality of Life questionnaires survey scale was used among 600 primary school teachers in the mountain area.
    Double data entry with Epidata 3.02, and analysis of the Pearson, Kendall, Spearman correlation of 535 effective cases with SPSS 16.0
    were carried out on the basis of the correlation coefficient r and related degree judge correlation. Results: The questionnaire effective
    rate was 97.99%, and questionnaire Cronbachs'a was 0.768. Analysis of variance(F= 7 855.669, P = 0.000 < 0.01)was in accordance
    with normal distribution continuity. MOF2, 12, 14 of primary school teachers' life style and SF-36 Quality of Life scale of 9 dimensions
    have negative correlation relationship. MOF5 and SF-36 Quality of Life scale of 9 dimensions have positive correlation. Conclusion:
    Intervention, guidance and improvement of equipment from MOF2, 12, 14 and MOF 5 can help the development of primary school
    teachers' quality of life.

    The Health Education of 125I Seed Esophageal Stents Implantation on Patients with Esophageal Cancer
    Zhao Juanjuan, Xu Song, Xiang Shutian, Song Fang, Duan Baofeng
    2017, 2(2):  80-82. 
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    Objective: To explore the health education of 125I seed esophageal stents implantation on patients with esophageal cancer.
    Methods: Formal health education was given to 12 patients with advanced esophageal cancer before and after the implantation. The
    effect was summarized and analyzed. Results: 125I seed esophageal stents were successfully implanted in 12 patients with advanced
    esophageal cancer. After surgery, the patients were calm and cooperative in surgery. After surgery, there were no serious complications.
    Conclusion: It is of vital importance to give formal health education to patients with 125I seed esophageal stents. This is an important
    method to ensure the success of surgery and reduce postoperative complications.

    Evaluation of the Effect of Standardized Nursing on Temporary Central Vena Catheterization
    Kang Kaiyuan, Wang Xiumin, Deng Cheng'ai, Chen Qian, Li Yanfang, Qin Ling
    2017, 2(2):  83-86. 
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    Objective: To investigate the effect of standardized hemodialysis nursing on temporary Central Vena Catheterization
    (CVC). Methods: Retrospective Analysis of the situation of 240 cases of using temporary CVC in hemodialysis in Department of
    Nephrology of The First People's Hospital of Zhaotong from January 2013 to December 2014. The nursing methods were summarized
    and the effect was analyzed. Results: It's found 179 cases(74.6%)of right jugular hepatic, 55 cases(22.9%)of right femoral vein, 4
    cases(1.7%)of left femoral vein, and 2 cases(0.8%)of left jugular hepatic. With the blood flow velocity at 160-260 mL/min, right
    jugular hepatic was better than right femoral vein. 17 cases(7.1%)met the infection diagnostic code of CVC, and 158 adverse events
    (3.5%)were dealt with appropriately without coagulation in hemodialyzer and other complication. Conclusion: Standardized nursing
    can low the dysfunction of temporary CVC and make sure the safety of hemodialysis, which is worthy of generalization.

    Nursing Intervention in Process of Smoking Cessation for Patient with COPD
    Dong Jiao
    2017, 2(2):  87-89. 
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    Objective: To explore the role of nursing intervention in process of smoking cessation for patients with COPD and to
    provide a theoretical foundation for nursing work. Methods: Using the random grouping method, 70 COPD patients who were in
    hospital from March to July in 2014 were divided into observation group and control group with 35 patients in each group randomly.
    The observation group received the comprehensive nursing intervention, while the control group used the traditional mode. We had
    observed the smoking situation in this two group patients for 1 year. Results: The success ratio of smoking cessation in observation
    group reached to 60.0%(21/35)and the success ratio in control group is 35.3%(12/34)except 1 case lost. The result is significance
    different(P<0.05). Conclusion: Psychological behavior intervention, speech of successful smoking cessation and follow-up phone
    calls are the effective measures that increased the success ratio of stopping cessation in patients with COPD, which is worthy of
    popularization.

    Research on the Status Quo of Chinese Language Learning of International MBBS Students
    in Dali University
    Wang Jing
    2017, 2(2):  90-92. 
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    The key of international students education lies in the quality of education, especially in establishing and improving
    Chinese language teaching. Through analyzing the present Chinese language learning situation of International MBBS students studying
    in Dali University, this paper proposes solutions aiming to promote the quality of international students teaching.

    Investigation on Post-Traumatic Stress Disorder of International Students
    Zhou Wanqing
    2017, 2(2):  93-95. 
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    Objective: To analyze the characteristics of post-traumatic stress disorder of international students. Methods: Civilian
    version post- traumatic stress disorder survey scale(PCLS- C) was used in the survey in Yunnan University, Yunnan Normal
    University, and Dali University. Results: There are regional differences, intercollegiate differences, gender differences, age differences,
    educational differences and cause differences in the international students' positive predictive value of PTSD. And the regional
    differences, intercollegiate differences, gender differences and cause differences are statistically significant(P<0.05). Conclusion:
    The PTSD positive detection rate of those who lived in the closer distance to where disaster occurred, and those who directly or
    indirectly underwent a disaster, as well as the female international students was rather higher. The PTSD positive detection rate of those
    who have relatively more mature psychology, more abundant knowledge, better ability structure was rather lower. We should improve
    international students' psychological quality, perfect their knowledge and ability structure, improve their ability to cope with sudden
    catastrophic event. We should pay special attention and give special support to the post-traumatic stress disorder of young international
    students, undergraduate international students, and female international students.

    On the Construction of Medical Teachers' Team of Dali University from the Perspective of
    Education Internationalization
    Guo Xianguo
    2017, 2(2):  96-100. 
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    Objective: To discuss the existing problems and difficulties in medical teachers team of Dali University from the
    perspective of internationalization of higher education. Methods: Through some observations in Hong Kong Polytechnic University, the
    status of medical teachers team of Dali University was compared and analyzed. Results: Dali University has been facing a great
    difficulty in rather low academic ability and low English proficiency level in medical teachers team, and difficulty in recruiting and
    employing medical talents with doctor's degree(Ph.D). Most teachers have no experience of studying abroad and hardly can get used
    to the trend of interationalization of education. Conclusion: The English training for medical teachers at home and abroad is very
    necessary in order to meet the needs of MBBS program and education internationalization.